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Fig. 7 | Journal of Neuroinflammation

Fig. 7

From: Microglia prevent peripheral immune cell invasion and promote an anti-inflammatory environment in the brain of APP-PS1 transgenic mice

Fig. 7

Gene expression analysis in the brain after PLX5622 treatment. Gene transcription was successfully downregulated for several microglia, pro-inflammatory, anti-inflammatory, and phagocytosis-relevant genes upon microglia ablation in the hippocampus (a) and cortex (b) of WT and APP-PS1 mice. Two-way ANOVA with Tukey’s multiple comparison test (n = 6–8/group) was performed

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