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Table 2 Effect of Pb exposure on short-term spatial memory (probe test) of Wistar rat pups at PND30 and PND45

From: Intraventricular infusion of quinolinic acid impairs spatial learning and memory in young rats: a novel mechanism of lead-induced neurotoxicity

 

PND30

PND45

Control

Pb-exposed

Control

Pb-exposed

Zone time (s)

15.9 ± 0.84

10.5 ± 1.7*

18.6 ± 1.9

11.6 ± 1.1*

Entry latency (s)

8.6 ± 1.8

15.9 ± 2.7*

5.1 ± 0.8

8.4 ± 1.6*

Distance (cm)

345.0 ± 40.7

212.8 ± 33.6*

293.6 ± 53.4

313.0 ± 28.8

N

10

14

9

13

  1. Data shown as mean ± SEM. *Significantly different from respective control (p < 0.05) by Student’s t test for two independent samples with unequal variance
  2. Zone time: Total amount of time (in sec) that the subject’s center of gravity spent in the target zone during the current trial. Entry latency: Time (in sec) before the subject’s center of gravity entered the target zone during the current trial. Distance: distance traveled (cm) by the subject within the target zone
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Journal of Neuroinflammation

ISSN: 1742-2094