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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: LGI1 expression and human brain asymmetry: insights from patients with LGI1-antibody encephalitis

Fig. 2

Hemispheric asymmetry of LGI1 expression in the human brain samples. a In the hippocampus, the western blotting and optical density analysis revealed no significant difference in LGI1 expression between both hemispheres (relative LGI1 expression of left/right = 1.39 ± 1.26, P = 0.653). Four samples (1, 5, 8, and 9) had higher LGI1 expression on the left side. b In the globus pallidus, the LGI1 expression was significantly increased on the left hemisphere (relative LGI1 expression of left/right = 1.97 ± 1.08, P = 0.019). All samples, except one (1), had higher LGI1 expression on the left side. The box plots show the median (line), interquartile ranges (boxes), and minimum to maximum (whiskers). P values were calculated using Wilcoxon matched pairs signed-rank test. *P < 0.05

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