Table 3 Systemic response to cardiac surgery
Placebo (n = 15) | Methylprednisolone (n = 15) | Between group analysis, p value | |||
|---|---|---|---|---|---|
Preoperative | Postoperative | Preoperative | Postoperative | ||
Serum TNF-α (ng/L)# | 2.45 (0.88) | 2.15 (0.68) | 2.36 (1.14) | 1.54 (0.83)*** | < 0.001 |
Serum IL-6 (ng/L)# | 0.86 (0.82) | 49.1 (48)*** | 0.99 (0.85) | 14.6 (8.8)*** | < 0.001 |
Serum IL-8 (ng/L) | 14.2 ± 5.4 | 40.9 ± 23*** | 12.4 ± 4.8 | 19.2 ± 15 | 0.004 |
Serum S-100B (μg/L)# | 0.060 (0.027) | 0.116 (0.07)* | 0.044 (0.03) | 0.126 (0.06)** | 0.48 |
Serum albumin (g/L) | 43.2 ± 4.8 | 35.1 ± 4.5*** | 43.2 ± 3.3 | 35.9 ± 2.9*** | 0.65 |
Serum NSE (μg/L)# | 14.9 (14) | 27.6 (7.6)* | 13.8 (8.2) | 31.1 (12)* | 0.27 |