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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Leukemia inhibitory factor modulates the peripheral immune response in a rat model of emergent large vessel occlusion

Fig. 4

LIF does not alter splenic IL-12 p40 levels after MCAO. Western blotting was used to measure levels of the IL-12 p40 subunit in the spleen 72 h after sham surgery and MCAO. a There was no significant overall change in IL-12 p40 levels after MCAO and LIF treatment, but there was a trend towards decreased IL-12 p40 levels in the MCAO + LIF group compared to the sham and MCAO + PBS groups that approached significance. b When IL-12 p40 levels were normalized to spleen weights, there was a trend towards increased IL-12 p40 in the MCAO + PBS group compared to the MCAO + LIF and sham groups. n = 8 animals per treatment group

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