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Fig. 9 | Journal of Neuroinflammation

Fig. 9

From: Leukemia inhibitory factor modulates the peripheral immune response in a rat model of emergent large vessel occlusion

Fig. 9

IFNγ release in the spleen decreases after MCAO and LIF treatment. IFNγ release in spleen tissue was measured using an ELISA kit and normalized to the total protein concentration. a At 72 h after MCAO or sham surgery, there was a significant decrease in IFNγ release after MCAO + PBS treatment (*p < 0.05) and MCAO + LIF treatment (**p < 0.01) compared to sham levels. There was also a significant decrease in IFNγ release after MCAO + LIF treatment compared to the MCAO + PBS group (*p < 0.05). b When IFNγ levels were normalized to spleen weights, normalized IFNγ was significantly higher in the MCAO + PBS group compared to the sham or MCAO + LIF groups. n = 8 animals per treatment group

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Journal of Neuroinflammation

ISSN: 1742-2094