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Table 2 CSF sTREM2 Spearman’s Rho correlations in the hip fracture cohort

From: CSF sTREM2 in delirium—relation to Alzheimer’s disease CSF biomarkers Aβ42, t-tau and p-tau

 

PATIENTS WITHOUT DEMENTIA

PATIENTS WITH DEMENTIA

 

All

No delirium

Delirium

All

No delirium

Delirium

N

59

44

15

61 (60)

10

50

 

Rho

p

Rho

p

Rho

p

Rho

p

Rho

p

Rho

p

Age

0.21

0.12

0.12

0.43

0.23

0.40

0.00

0.98

0.16

0.66

-0.05

0.74

Time to surgery (hours) *

0.01

0.93

-0.03

0.83

0.06

0.84

0.39

0.002

0.43

0.21

0.40

0.005

CSF Biomarkers

N

57

 

44

 

13

 

60

 

9

 

50

 
 

Rho

p

Rho

p

Rho

p

Rho

p

Rho

p

Rho

p

CSF Aβ42 (pg/ml)

0.11

0.40

0.20

0.18

0.31

0.30

0.40

0.002

0.02

0.97

0.53

<0.001

CSF Aβ38 (pg/ml) MSD

0.09

0.49

0.06

0.71

0.18

0.55

0.44

<0.001

0.40

0.29

0.45

0.001

CSF Aβ40 (pg/ml) MSD

0.14

0.32

0.12

0.44

0.23

0.45

0.48

<0.001

0.37

0.33

0.51

<0.001

CSF Aβ42 (pg/ml) MSD

0.09

0.52

0.24

0.12

-0.13

0.67

0.43

0.001

0.15

0.70

0.53

<0.001

CSF t-tau (pg/ml)

0.14

0.28

-0.04

0.82

0.20

0.51

0.46

<0.001

0.83

0.005

0.34

0.016

CSF p-tau (pg/ml)

0.12

0.38

-0.02

0.90

0.23

0.46

0.49

<0.001

0.77

0.016

0.37

0.008

  1. Aβ42, amyloid beta 1–42; t-tau, total-tau; p-tau, phosphorylated tau; sTREM2, soluble triggering receptor expressed on myeloid cells
  2. *Time to surgery, hours from hospital admission to surgery (onset of anesthesia) and CSF sampling