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Table 2 CSF protein levels of inflammatory markers, total tau, and albumin index

From: Cerebrospinal fluid pro-inflammatory cytokines differentiate parkinsonian syndromes

Analyte

PD

MSA

PSP

Controls (SC)

CRP, mean (SD)b

5376.31 (4376.71)

8208.5 (3921.46)

8293.99 (4261.78)

6005.12 (4155.4)

IFN-γ, mean (SD)

1.35 (1.69)

1.33 (1.04)

2.11 (2.37)

3.09 (10.64)

IL-10, mean (SD)

4.57 (7.02)

4.71 (2.49)

6.18 (3.85)

5.66 (6.5)

IL-18, mean (SD)

47.85 (18.06)

53.25 (34.44)

50.52 (21.20)

45.30 (19.25)

IL-1β, mean (SD)b

2.82 (3.52)

3.58 (2.23)

4.96 (3.85)

2.60 (1.61)

IL-4, mean (SD)b

2.50 (2.21)

3.60 (2.22)

4.86 (3.90)

2.95 (1.90)

IL-6, mean (SD)b

53.41 (59.32)

86.98 (73.0)

102.53 (87.87)

61.74 (59.18)

TGF-β1, mean (SD)

1482.25 (407.20)

1435.18 (298.70)

1502.96 (416.43)

1518.89 (395.04)

TNF-α, mean (SD)b

79.78 (63.71)

106.80 (50.55)

127.21 (75.32)

87.65 (63.39)

Total tau protein, mean (SD)b

303.9 (213.9)

470.8 (242.6)

365.8 (187.5)

286.8 (196.4)

CSF protein, total, g/L, mean

0.53

0.52

0.54

0.42

CSF leukocytes, total, mean

2.91

1.50

2.16

2.60

Albumin index, mean

8.13

8.32

8.38

6.31

  1. aKruskal-Wallis p < 0.05, Bonferroni corrected
  2. bp < 0.05 chi-square. All concentrations are in pg/ml, with the exception of CSF protein