Table 1 Ketogenic and control mouse indices
Mice | Baseline IOP (mmHg) | Terminal IOP (mmHg) | Baseline weight (g) | Terminal weight (g) | Food intake by week (g) | kCal by week | Plasma βHB levels (mM) | |
|---|---|---|---|---|---|---|---|---|
Keto D2 | Male (n = 10) | 17.2 ± 1.3 | 18.5 ± 1.3 | 33.2 ± 1.7 | 40.2 ± 2.1 | 18.5 ± 0.7 | 116.5 ± 0.8 | 0.53 ± 0.042 |
Female (n = 8) | 16.5 ± 0.8 | 17.4 ± 1.2 | 26.6 ± 0.8 | 29.5 ± 1.5 | 12.5 ± 0.4 | 78.7 ± 1.5 | 0.40 ± 0.03 | |
Control D2 | Male (n = 10) | 17.5 ± 0.2 | 18.1 ± 0.8 | 32.2 ± 1.4 | 32.0 ± 1.2 | 30.5 ± 1.2 | 119.8 ± 1.1 | 0.102 ± 0.01 |
Female (n = 6) | 16.4 ± 1.0 | 17.5 ± 1.0 | 26.5 ± 0.9 | 26.1 ± 1.2 | 24.5 ± 1.6 | 95.5 ± 1.2 | 0.090 ± 0.04 | |
D2G | Male (n = 3) | 12.5 ± 0.1 | 12.2 ± 0.1 | 30.5 ± 1.5 | 31.0 ± 1.5 | 29.5 ± 1.5 | 115.5 ± 1.4 | 0.07 ± 0.01 |
Female (n = 3) | 12.1 ± 0.2 | 11.8 ± 0.2 | 25.5 ± 1.0 | 26.2 ± 1.1 | 22.1 ± 1.2 | 86.2 ± 1.3 | 0.06 ± 0.02 | |