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Table 1 Demographical characteristics

From: In vivo assessment of neuroinflammation in progressive multiple sclerosis: a proof of concept study with [18F]DPA714 PET

 

Patients (n = 8)

Healthy controls (n = 7)

Age, mean and SD (years)

53.1 ± 2.7

52.0 ± 4.1

Gender, male/female

3/5

3/4

Genotype, HAB/MAB

4/4

3/4

Subtype MS, PPMS/SPMS

5/3

N/A

Disease duration, mean and SD (years)

13.1 ± 9.4

N/A

EDSS, median and range

5.0 (4.0–6.0)

N/A

PASAT-3 score, mean and SD

45.8 ± 10.8

49.6 ± 12.5

SDMT score, mean and SD

44.0 ± 11.9

55.0 ± 13.5

T2 lesion volume, median and range (cm3)

14.3 (3.6–60.6)

N/A

  1. Abbreviations: EDSS Expanded Disability Status Scale, HAB genetic high-affinity binder, MAB genetic medium-affinity binder, PASAT Paced Auditory Serial Addition Test, PPMS primary progressive multiple sclerosis, SDMT Symbol Digit Modalities Test, SPMS secondary progressive multiple sclerosis