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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: A central role for P2X7 receptors in human microglia

Fig. 3

ATP-gated currents facilitate. a Representative tracing of facilitating inward currents recorded from successive applications of 10 mM ATP (3 s duration) separated by 15-s intervals, from a holding potential of − 60 mV. b Time course of facilitation measured as the fraction of current recorded at the end of each successive 3-s ATP application over the initial current (n = 25 cells). c Tracing of microglial facilitation recorded from successive applications of 5 mM ATP (15 s duration) separated by 30-s intervals, from a holding potential of − 60 mV. d Time course of facilitation measured as the fraction of current recorded at the end of each successive 15-s ATP application over the initial current (n = 7 cells)

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