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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: STING-mediated type-I interferons contribute to the neuroinflammatory process and detrimental effects following traumatic brain injury

Fig. 4

Genetic ablation of STING confers neuroprotection 24 h after TBI. Total lesion volumes of wild-type and STING−/− mice were assessed by TTC staining and quantified using Image J. a Representative images demonstrating reduced infarct size in STING−/− compared to wild-type mice 24 h after CCI (n = 6). b Quantification of (a) showing STING−/− mice have significantly reduced lesion volumes compared to WT mice 24 h after CCI. Data represents mean ± SEM, p < *0.05; n = 6 animals per group. Scale bar: 1 mm

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