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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Preemptive intrathecal administration of endomorphins relieves inflammatory pain in male mice via inhibition of p38 MAPK signaling and regulation of inflammatory cytokines

Fig. 5

Immunostaining analysis showed that the expression of the mu-opioid receptor is significantly increased after CFA. Photomicrographs of representative L4 DRG neurons illustrated the mu-opioid receptor immunoreactivity neurons (green) in the control group (Control) and CFA group (CFA). Arrows indicate the mu-opioid receptor positive neurons, and triangles indicate the negative neurons. n = 4–6 animals/group, ***P < 0.001 indicates significant differences compared with the control group according to two-tailed t test. Scale bar = 50 μm

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