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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Persistent reduction in sialylation of cerebral glycoproteins following postnatal inflammatory exposure

Fig. 5

a-d Representative HPLC chromatograms of glycan chains of rat brain GSLs labelled with anthranilic acid. Panels show representative chromatograms of P4 Sham (n=2) (a), P24 Sham (n=2) (b), P4 LPS (n=2) (c) and P24 LPS (n=2) (d) samples, with fluorescence intensity (arbitrary) shown on the y-axis. e, f Levels of gangliosides measured by quantification of HPLC chromatograms. (e) Comparison of relative compositions of LacCer, GM3, GM1, GD3, GD1a, GD1b, GT1a, GT1b and GQ1 gangliosides in P4 LPS and Sham brains. (f) Relative compositions of LacCer, GM3, GM1, GD3, GD1a, GD1b, GT1a and GT1b gangliosides in P24 LPS and Sham brains. Values represent means ± S.D. of duplicate (P4) or triplicate (P24) measurements

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Journal of Neuroinflammation

ISSN: 1742-2094