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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: The GLP-1 analog, liraglutide prevents the increase of proinflammatory mediators in the hippocampus of male rat pups submitted to maternal perinatal food restriction

Fig. 1

Body weight gain of pregnant dams throughout the food restriction protocol, from mating until day 21 of gestation. Pregnant rats were randomly submitted to food restriction (50% of daily intake of control dams/MPFR) from gestational day 12 or were fed ad libitum in the control group (CT; see arrow). From gestational day 14 to parturition, dams were treated with liraglutide (LIRA; 100 μg/kg/12 h, see arrow) or vehicle. Data are mean + SEM. (MPFR/VEH compared to CT/VEH: *p < 0.05, **p < 0.01, ****p < 0.0001; MPFR/VEH compared to CT/LIRA: &p < 0.05, &&p < 0.01, &&&&p < 0.0001; MPFR/LIRA compared to CT/VEH: aap < 0.01, aaap < 0.001, aaaap < 0.0001; MPFR/LIRA compared to CT/LIRA: bbbp < 0.001, bbbbp < 0.0001)

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Journal of Neuroinflammation

ISSN: 1742-2094