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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: The GLP-1 analog, liraglutide prevents the increase of proinflammatory mediators in the hippocampus of male rat pups submitted to maternal perinatal food restriction

Fig. 6

Proinflammatory mediators in male offspring. a Interleukin-1b (IL1b). b Interleukin-6 (IL-6). c Nuclear factor-κB (NF-κB). d Major histocompatibility complex-II (MHCII). e Interleukin-10 (IL10). f Transforming growth factor β (TGFβ). g Arginase 1 (ARG1) mRNA levels in the hippocampus. CT/VEH, control pups treated with vehicle; CT/LIRA, control pups treated with liraglutide; MPFR/VEH, food-restricted pups treated with vehicle; MPFR/LIRA, food-restricted pups treated with liraglutide. Data are mean + SEM. (*p < 0.05 compared to CT/VEH; **p < 0.01 compared to CT/VEH; &p < 0.05 compared to CT/LIRA; &&p < 0.01 compared to CT/LIRA; #p < 0.05 compared to MPFR/VEH; ##p < 0.01 compared to MPFR/VEH)

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Journal of Neuroinflammation

ISSN: 1742-2094