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Table 2 Effect of LPS and LPS + PLX5622 in cytokine levels in the blood plasma

From: Colony-stimulating factor 1 receptor inhibition prevents disruption of the blood-retina barrier during chronic inflammation

 

12 h

24 h

96 h

LPS

LPS + PLX5622

LPS

LPS + PLX5622

LPS

LPS + PLX5622

CXCL1

1.14

1.40

1.69

4.18***###

2.20***

5.02**

G-CSF

12.95***

9.76***#

21.94***

30.59***##

6.49***

22.72***##

IL-4

0.88

0.43**

1.16

1.15

10.31***

16.85***

MMP-3

0.92

0.94

1.82*

3.64***##

8.06**

27.62***###

  1. All data are normalized to control plasma samples.*p < 0.05, **p < 0.01, ***p < 0.001 compared to control; #p < 0.05, ##p < 0.01, ###p < 0.001 compared to LPS
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Journal of Neuroinflammation

ISSN: 1742-2094