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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: IL-17A contributes to perioperative neurocognitive disorders through blood-brain barrier disruption in aged mice

Fig. 6

Anti-IL-17A Abs reversed the surgery-induced decrease of occludin and claudin-5 levels in the hippocampus. a The expression levels of occludin and claudin-5 in the hippocampus detected by immunostaining. Scale bar, 200 μm. b Quantification of occludin-positive and claudin-positive cells in the CA1 area of the hippocampus. c The expression levels of occludin and claudin-5 in the hippocampus detected by Western blot. d Quantification of occludin and claudin-5 levels. *P < 0.05 and **P < 0.01 versus the Con group. ##P < 0.01 versus the Sur group. Data are presented as the mean ± SEM (n = 4)

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Journal of Neuroinflammation

ISSN: 1742-2094