Fig. 7

Anti-IL-17A Abs inhibited the expression of MMP-2 and MMP-9 induced by surgery. a Immunostaining was used to detect the levels of MMP-2 and MMP-9 in the CA1 area of the hippocampus. Scale bar, 200 μm. b Quantification of MMP-2-positive and MMP-9-positive cells in the CA1 area of the hippocampus. c The expression levels of MMP-2 and MMP-9 in the hippocampus detected by Western blot. d Quantification of MMP-2 and MMP-9 levels. *P < 0.05 and **P < 0.01 versus the Con group. ^##P < 0.01 versus the Sur group. Data are presented as the mean ± SEM (n = 4)