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Fig. 9 | Journal of Neuroinflammation

Fig. 9

From: IL-17A contributes to perioperative neurocognitive disorders through blood-brain barrier disruption in aged mice

Fig. 9

IL-17A decreased occludin and claudin-5 levels and increased MMP-2 and MMP-9 levels in bEnd.3 cells. a The expression levels of occludin and claudin-5 in bEnd.3 cells 24 h after treatment with different doses of IL-17A detected by Western blot. b Quantification of occludin and claudin-5 in bEnd.3 cells. c The expression levels of MMP-2 and MMP-9 in bEnd.3 cells 24 h after treatment with different doses of IL-17A detected by Western blot. d Quantification of MMP-2 and MMP-9 levels in bEnd.3 cells. All experiments were repeated three times. *P < 0.05 and **P < 0.01 versus the control group. Data are presented as the mean ± SEM

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