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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Early treatment with minocycline following stroke in rats improves functional recovery and differentially modifies responses of peri-infarct microglia and astrocytes

Fig. 6

Effects of lower dose minocycline treatment on infarct volume and forelimb function after photothrombotic stroke. a Infarct volume: Two-way analysis of variance revealed no significant effect of the minocycline treatment but a significant effect of time after stroke (p < 0.01; n = 4–8 per group). b Box plot of results from the forelimb placing test. Outliers are indicated with open circles. n = 6 per group for all times except 3 h which shows the pooled data for rats in each of the subsequent groups. Rate of recovery was faster at 3 days *p < 0.05 (Minocycline vs vehicle, Mann-Whitney U test analysis of area under curve for those rats tested at both 3 h and 3 days). No significant differences were detected at other times

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