Fig. 8

Effect of higher-dose minocycline treatment on recovery of neurological function after photothrombotic stroke. Box plots of dysfunction and recovery up to 28 days after photothrombotic stroke in a the forelimb placing test and b the cylinder test. Outliers are shown as open circles (n = 8 per group). Recovery in the forelimb placing test was more rapid in minocycline-treated rats (p < 0.05; Mann-Whitney U test comparison of area under curve for time points between 3 h and 28 days.) There was no significant difference in recovery between 24 h and 28 days for performance in the cylinder test