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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Transplantation of mesenchymal stem cells genetically engineered to overexpress interleukin-10 promotes alternative inflammatory response in rat model of traumatic brain injury

Fig. 2

In vitro expression of IL-10 in transduced MSCs. a Representative immunocytochemistry images of MSCs with and without IL-10 overexpression. MSCs + IL10-GFP group appeared to have higher IL-10 immunofluorescent signal than MSCs + GFP group. b Mean integrated density of IL-10 showed that MSCs + IL-10 had significantly higher expression of IL-10 than MSCs + GFP (***p < 0.001). c RT-qPCR resulted in significant mean fold changes of IL-10 expression in MSCs + IL-10 group in comparison to MSCs + GFP (**p < 0.01). d Western blot IL-10 levels were compared between the two MSC groups. e MSCs + IL-10-GFP cells expressed a significantly higher amount of IL-10 level in comparison to MSCs + GFP (*p < 0.05; scale bar = 50 μm). Error bars represent standard error of the mean (± SEM)

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