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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Fluoxetine attenuates neuroinflammation in early brain injury after subarachnoid hemorrhage: a possible role for the regulation of TLR4/MyD88/NF-κB signaling pathway

Fig. 2

Fluoxetine downregulated MMP-9 expression and prevented degradation of the tight junction proteins in the ipsilateral cortex at 24 h after SAH. a Representative western blot bands of MMP-9, occludin, claudin-5, and ZO-1. b Densitometric quantification of MMP-9. **p < 0.01 vs sham. ##p < 0.01 vs SAH+vehicle. n = 6/group. c Densitometric quantification of occludin. **p < 0.01 vs sham. #p < 0.05 vs SAH+vehicle. n = 6/group. d Densitometric quantification of claudin-5. **p < 0.01 vs sham. ##p < 0.01 vs SAH+vehicle. n = 6/group. e Densitometric quantification of ZO-1. **p < 0.01 vs sham. #p < 0.05 vs SAH+vehicle. n = 6/group

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