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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Long-term characterization of activated microglia/macrophages facilitating the development of experimental brain metastasis through intravital microscopic imaging

Fig. 1

3D distribution of M/Ms during melanoma brain metastasis. a Intravital microscopic images of brains with melanoma metastasis in the same mice after RFP-B16 injection. Red: RFP, green: EGFP. Scale bar: 20 μm. b HE staining of brain tissue sections with metastasis after RFP-B16 injection. Scale bar: 100 μm. The white dotted line identifies the tumor area. c Representative results for the 3D distribution of M/Ms on day 1 and day 21 after RFP-B16 or PBS injection. The white dotted line refers to the lumen of blood vessels. Scale bar: 50 μm. d Volume density of M/Ms from the RFP-B16 (upper panel) or PBS (lower panel) injection group; n = 6 mice per group. The data are presented as the mean ± SEM

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Journal of Neuroinflammation

ISSN: 1742-2094