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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Loss of Par1b/MARK2 primes microglia during brain development and enhances their sensitivity to injury

Fig. 2

Loss of Par1b increases microglia density in vivo. a Representative images of CX3CR1-GFP-positive Par1b (+/+) and (+/−) mice at P5, P9, P30, and P120 within the parietal association cortex. Scale bar = 20 μm. b Quantification of microglial density. CX3CR1-GFP-positive Par1b (+/−) mice show a significant increase in microglia density at P5, P9, and P120, with the trend holding at P30. n (animals) = Par1b (+/+) P5(6), P9(7), P30(5), P120(7); Par1b (+/−) P5(7), P9(3), P30(5), P120(5), **p < 0.01, ***p < 0.001 by one-way ANOVA

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