TY - JOUR AU - Burrows, G. G. PY - 2005 DA - 2005// TI - Systemic immunomodulation of autoimmune disease using MHC-derived recombinant TCR ligands JO - Curr Drug Targets Inflamm Allergy VL - 4 UR - https://doi.org/10.2174/1568010053586363 DO - 10.2174/1568010053586363 ID - Burrows2005 ER - TY - JOUR AU - Burrows, G. G. AU - Chang, J. W. AU - Bachinger, H. P. AU - Bourdette, D. N. AU - Offner, H. AU - Vandenbark, A. A. PY - 1999 DA - 1999// TI - Design, engineering and production of functional single-chain T cell receptor ligands JO - Protein Eng VL - 12 UR - https://doi.org/10.1093/protein/12.9.771 DO - 10.1093/protein/12.9.771 ID - Burrows1999 ER - TY - JOUR AU - Offner, H. AU - Sinha, S. AU - Wang, C. AU - Burrows, G. G. AU - Vandenbark, A. A. PY - 2008 DA - 2008// TI - Recombinant T cell receptor ligands: immunomodulatory, neuroprotective and neuroregenerative effects suggest application as therapy for multiple sclerosis JO - Rev Neurosci VL - 19 UR - https://doi.org/10.1515/REVNEURO.2008.19.4-5.327 DO - 10.1515/REVNEURO.2008.19.4-5.327 ID - Offner2008 ER - TY - JOUR AU - Burrows, G. G. AU - Adlard, K. L. AU - Bebo, B. F. AU - Chang, J. W. AU - Tenditnyy, K. AU - Vandenbark, A. A. AU - Offner, H. PY - 2000 DA - 2000// TI - Regulation of encephalitogenic T cells with recombinant TCR ligands JO - J Immunol VL - 164 UR - https://doi.org/10.4049/jimmunol.164.12.6366 DO - 10.4049/jimmunol.164.12.6366 ID - Burrows2000 ER - TY - JOUR AU - Burrows, G. G. AU - Chou, Y. K. AU - Wang, C. AU - Chang, J. W. AU - Finn, T. P. AU - Culbertson, N. E. AU - Kim, J. AU - Bourdette, D. N. AU - Lewinsohn, D. A. AU - Lewinsohn, D. M. PY - 2001 DA - 2001// TI - Rudimentary TCR signaling triggers default IL-10 secretion by human Th1 cells JO - J Immunol VL - 167 UR - https://doi.org/10.4049/jimmunol.167.8.4386 DO - 10.4049/jimmunol.167.8.4386 ID - Burrows2001 ER - TY - JOUR AU - McMahan, R. H. AU - Watson, L. AU - Meza-Romero, R. AU - Burrows, G. G. AU - Bourdette, D. N. AU - Buenafe, A. C. PY - 2003 DA - 2003// TI - Production, characterization, and immunogenicity of a soluble rat single chain T cell receptor specific for an encephalitogenic peptide JO - J Biol Chem VL - 278 UR - https://doi.org/10.1074/jbc.M300628200 DO - 10.1074/jbc.M300628200 ID - McMahan2003 ER - TY - JOUR AU - Huan, J. AU - Subramanian, S. AU - Jones, R. AU - Rich, C. AU - Link, J. AU - Mooney, J. AU - Bourdette, D. N. AU - Vandenbark, A. A. AU - Burrows, G. G. AU - Offner, H. PY - 2004 DA - 2004// TI - Monomeric recombinant TCR ligand reduces relapse rate and severity of experimental autoimmune encephalomyelitis in SJL/J mice through cytokine switch JO - J Immunol VL - 172 UR - https://doi.org/10.4049/jimmunol.172.7.4556 DO - 10.4049/jimmunol.172.7.4556 ID - Huan2004 ER - TY - JOUR AU - Sinha, S. AU - Subramanian, S. AU - Miller, L. AU - Proctor, T. M. AU - Roberts, C. AU - Burrows, G. G. AU - Vandenbark, A. A. AU - Offner, H. PY - 2009 DA - 2009// TI - Cytokine switch and bystander suppression of autoimmune responses to multiple antigens in experimental autoimmune encephalomyelitis by a single recombinant T-cell receptor ligand JO - J Neurosci VL - 29 UR - https://doi.org/10.1523/JNEUROSCI.5812-08.2009 DO - 10.1523/JNEUROSCI.5812-08.2009 ID - Sinha2009 ER - TY - JOUR AU - Offner, H. AU - Subramanian, S. AU - Wang, C. AU - Afentoulis, M. AU - Vandenbark, A. A. AU - Huan, J. AU - Burrows, G. G. PY - 2005 DA - 2005// TI - Treatment of passive experimental autoimmune encephalomyelitis in SJL mice with a recombinant TCR ligand induces IL-13 and prevents axonal injury JO - J Immunol VL - 175 UR - https://doi.org/10.4049/jimmunol.175.6.4103 DO - 10.4049/jimmunol.175.6.4103 ID - Offner2005 ER - TY - JOUR AU - Wang, C. AU - Gold, B. G. AU - Kaler, L. J. AU - Yu, X. AU - Afentoulis, M. E. AU - Burrows, G. G. AU - Vandenbark, A. A. AU - Bourdette, D. N. AU - Offner, H. PY - 2006 DA - 2006// TI - Antigen-specific therapy promotes repair of myelin and axonal damage in established EAE JO - J Neurochem VL - 98 UR - https://doi.org/10.1111/j.1471-4159.2006.04081.x DO - 10.1111/j.1471-4159.2006.04081.x ID - Wang2006 ER - TY - JOUR AU - Sinha, S. AU - Subramanian, S. AU - Proctor, T. M. AU - Kaler, L. J. AU - Grafe, M. AU - Dahan, R. AU - Huan, J. AU - Vandenbark, A. A. AU - Burrows, G. G. AU - Offner, H. PY - 2007 DA - 2007// TI - A promising therapeutic approach for multiple sclerosis: recombinant T-cell receptor ligands modulate experimental autoimmune encephalomyelitis by reducing interleukin-17 production and inhibiting migration of encephalitogenic cells into the CNS JO - J Neurosci VL - 27 UR - https://doi.org/10.1523/JNEUROSCI.3599-07.2007 DO - 10.1523/JNEUROSCI.3599-07.2007 ID - Sinha2007 ER - TY - JOUR AU - Chang, J. W. AU - Mechling, D. E. AU - Bachinger, H. P. AU - Burrows, G. G. PY - 2001 DA - 2001// TI - Design, engineering, and production of human recombinant t cell receptor ligands derived from human leukocyte antigen DR2 JO - J Biol Chem VL - 276 UR - https://doi.org/10.1074/jbc.M101808200 DO - 10.1074/jbc.M101808200 ID - Chang2001 ER - TY - JOUR AU - Huan, J. Y. AU - Meza-Romero, R. AU - Mooney, J. L. AU - Chou, Y. K. AU - Edwards, D. M. AU - Rich, C. AU - Link, J. M. AU - Vandenbark, A. A. AU - Bourdette, D. N. AU - Bachinger, H. P. AU - Burrows, G. G. PY - 2005 DA - 2005// TI - Rationally designed mutations convert complexes of human recombinant T cell receptor ligands into monomers that retain biological activity JO - J Chem Technol Biotechnol VL - 80 UR - https://doi.org/10.1002/jctb.1086 DO - 10.1002/jctb.1086 ID - Huan2005 ER - TY - JOUR AU - Chou, Y. K. AU - Culbertson, N. AU - Rich, C. AU - LaTocha, D. AU - Buenafe, A. C. AU - Huan, J. AU - Link, J. AU - Wands, J. M. AU - Born, W. K. AU - Offner, H. PY - 2004 DA - 2004// TI - T-cell hybridoma specific for myelin oligodendrocyte glycoprotein-35-55 peptide produced from HLA-DRB1*1501-transgenic mice JO - J Neurosci Res VL - 77 UR - https://doi.org/10.1002/jnr.20201 DO - 10.1002/jnr.20201 ID - Chou2004 ER - TY - JOUR AU - Vandenbark, A. A. AU - Rich, C. AU - Mooney, J. AU - Zamora, A. AU - Wang, C. AU - Huan, J. AU - Fugger, L. AU - Offner, H. AU - Jones, R. AU - Burrows, G. G. PY - 2003 DA - 2003// TI - Recombinant TCR ligand induces tolerance to myelin oligodendrocyte glycoprotein 35-55 peptide and reverses clinical and histological signs of chronic experimental autoimmune encephalomyelitis in HLA-DR2 transgenic mice JO - J Immunol VL - 171 UR - https://doi.org/10.4049/jimmunol.171.1.127 DO - 10.4049/jimmunol.171.1.127 ID - Vandenbark2003 ER - TY - JOUR AU - Link, J. M. AU - Rich, C. M. AU - Korat, M. AU - Burrows, G. G. AU - Offner, H. AU - Vandenbark, A. A. PY - 2007 DA - 2007// TI - Monomeric DR2/MOG-35-55 recombinant TCR ligand treats relapses of experimental encephalomyelitis in DR2 transgenic mice JO - Clin Immunol VL - 123 UR - https://doi.org/10.1016/j.clim.2006.12.002 DO - 10.1016/j.clim.2006.12.002 ID - Link2007 ER - TY - JOUR AU - Vandenbark, A. A. AU - Meza-Romero, R. AU - Benedek, G. AU - Andrew, S. AU - Huan, J. AU - Chou, Y. K. AU - Buenafe, A. C. AU - Dahan, R. AU - Reiter, Y. AU - Mooney, J. L. PY - 2013 DA - 2013// TI - A novel regulatory pathway for autoimmune disease: binding of partial MHC class II constructs to monocytes reduces CD74 expression and induces both specific and bystander T-cell tolerance JO - J Autoimmun VL - 40 UR - https://doi.org/10.1016/j.jaut.2012.08.004 DO - 10.1016/j.jaut.2012.08.004 ID - Vandenbark2013 ER - TY - JOUR AU - Wang, C. AU - Mooney, J. L. AU - Meza-Romero, R. AU - Chou, Y. K. AU - Huan, J. AU - Vandenbark, A. A. AU - Offner, H. AU - Burrows, G. G. PY - 2003 DA - 2003// TI - Recombinant TCR ligand induces early TCR signaling and a unique pattern of downstream activation JO - J Immunol VL - 171 UR - https://doi.org/10.4049/jimmunol.171.4.1934 DO - 10.4049/jimmunol.171.4.1934 ID - Wang2003 ER - TY - JOUR AU - Offner, H. AU - Sinha, S. AU - Burrows, G. G. AU - Ferro, A. J. AU - Vandenbark, A. A. PY - 2011 DA - 2011// TI - RTL therapy for multiple sclerosis: a phase I clinical study JO - J Neuroimmunol VL - 231 UR - https://doi.org/10.1016/j.jneuroim.2010.09.013 DO - 10.1016/j.jneuroim.2010.09.013 ID - Offner2011 ER - TY - JOUR AU - Yadav, V. AU - Bourdette, D. N. AU - Bowen, J. D. AU - Lynch, S. G. AU - Mattson, D. AU - Preiningerova, J. AU - Bever, C. T. AU - Simon, J. AU - Goldstein, A. AU - Burrows, G. G. PY - 2012 DA - 2012// TI - Recombinant T-cell receptor ligand (RTL) for treatment of multiple sclerosis: a double-blind, placebo-controlled, phase 1, dose-escalation study JO - Autoimmune Dis VL - 2012 ID - Yadav2012 ER - TY - JOUR AU - Sinha, S. AU - Miller, L. AU - Subramanian, S. AU - McCarty, O. J. AU - Proctor, T. AU - Meza-Romero, R. AU - Huan, J. AU - Burrows, G. G. AU - Vandenbark, A. A. AU - Offner, H. PY - 2010 DA - 2010// TI - Binding of recombinant T cell receptor ligands (RTL) to antigen presenting cells prevents upregulation of CD11b and inhibits T cell activation and transfer of experimental autoimmune encephalomyelitis JO - J Neuroimmunol VL - 225 UR - https://doi.org/10.1016/j.jneuroim.2010.04.013 DO - 10.1016/j.jneuroim.2010.04.013 ID - Sinha2010 ER - TY - JOUR AU - Meza-Romero, R. AU - Benedek, G. AU - Yu, X. AU - Mooney, J. L. AU - Dahan, R. AU - Duvshani, N. AU - Bucala, R. AU - Offner, H. AU - Reiter, Y. AU - Burrows, G. G. AU - Vandenbark, A. A. PY - 2014 DA - 2014// TI - HLA-DRalpha1 constructs block CD74 expression and MIF effects in experimental autoimmune encephalomyelitis JO - J Immunol VL - 192 UR - https://doi.org/10.4049/jimmunol.1303118 DO - 10.4049/jimmunol.1303118 ID - Meza-Romero2014 ER - TY - JOUR AU - Sospedra, M. AU - Martin, R. PY - 2005 DA - 2005// TI - Immunology of multiple sclerosis JO - Annu Rev Immunol VL - 23 UR - https://doi.org/10.1146/annurev.immunol.23.021704.115707 DO - 10.1146/annurev.immunol.23.021704.115707 ID - Sospedra2005 ER - TY - JOUR AU - Steinman, L. PY - 2001 DA - 2001// TI - Multiple sclerosis: a two-stage disease JO - Nat Immunol VL - 2 UR - https://doi.org/10.1038/ni0901-762 DO - 10.1038/ni0901-762 ID - Steinman2001 ER - TY - JOUR AU - Frohman, E. M. AU - Racke, M. K. AU - Raine, C. S. PY - 2006 DA - 2006// TI - Multiple sclerosis--the plaque and its pathogenesis JO - N Engl J Med VL - 354 UR - https://doi.org/10.1056/NEJMra052130 DO - 10.1056/NEJMra052130 ID - Frohman2006 ER - TY - JOUR AU - Herrero-Herranz, E. AU - Pardo, L. A. AU - Gold, R. AU - Linker, R. A. PY - 2008 DA - 2008// TI - Pattern of axonal injury in murine myelin oligodendrocyte glycoprotein induced experimental autoimmune encephalomyelitis: implications for multiple sclerosis JO - Neurobiol Dis VL - 30 UR - https://doi.org/10.1016/j.nbd.2008.01.001 DO - 10.1016/j.nbd.2008.01.001 ID - Herrero-Herranz2008 ER - TY - JOUR AU - Steinman, L. PY - 1996 DA - 1996// TI - Multiple sclerosis: a coordinated immunological attack against myelin in the central nervous system JO - Cell VL - 85 UR - https://doi.org/10.1016/S0092-8674(00)81107-1 DO - 10.1016/S0092-8674(00)81107-1 ID - Steinman1996 ER - TY - JOUR AU - Benedek, G. AU - Meza-Romero, R. AU - Jordan, K. AU - Keenlyside, L. AU - Offner, H. AU - Vandenbark, A. A. PY - 2015 DA - 2015// TI - HLA-DRalpha1-mMOG-35-55 treatment of experimental autoimmune encephalomyelitis reduces CNS inflammation, enhances M2 macrophage frequency, and promotes neuroprotection JO - J Neuroinflammation VL - 12 UR - https://doi.org/10.1186/s12974-015-0342-4 DO - 10.1186/s12974-015-0342-4 ID - Benedek2015 ER - TY - JOUR AU - Jiang, Z. AU - Jiang, J. X. AU - Zhang, G. X. PY - 2014 DA - 2014// TI - Macrophages: a double-edged sword in experimental autoimmune encephalomyelitis JO - Immunol Lett VL - 160 UR - https://doi.org/10.1016/j.imlet.2014.03.006 DO - 10.1016/j.imlet.2014.03.006 ID - Jiang2014 ER - TY - JOUR AU - Mikita, J. AU - Dubourdieu-Cassagno, N. AU - Deloire, M. S. AU - Vekris, A. AU - Biran, M. AU - Raffard, G. AU - Brochet, B. AU - Canron, M. H. AU - Franconi, J. M. AU - Boiziau, C. AU - Petry, K. G. PY - 2011 DA - 2011// TI - Altered M1/M2 activation patterns of monocytes in severe relapsing experimental rat model of multiple sclerosis. Amelioration of clinical status by M2 activated monocyte administration JO - Mult Scler VL - 17 UR - https://doi.org/10.1177/1352458510379243 DO - 10.1177/1352458510379243 ID - Mikita2011 ER - TY - JOUR AU - Miron, V. E. AU - Franklin, R. J. PY - 2014 DA - 2014// TI - Macrophages and CNS remyelination JO - J Neurochem VL - 130 UR - https://doi.org/10.1111/jnc.12705 DO - 10.1111/jnc.12705 ID - Miron2014 ER - TY - JOUR AU - D'Arca, D. AU - Zhao, X. AU - Xu, W. AU - Ramirez-Martinez, N. C. AU - Iavarone, A. AU - Lasorella, A. PY - 2010 DA - 2010// TI - Huwe1 ubiquitin ligase is essential to synchronize neuronal and glial differentiation in the developing cerebellum JO - Proc Natl Acad Sci U S A VL - 107 UR - https://doi.org/10.1073/pnas.0912874107 DO - 10.1073/pnas.0912874107 ID - D'Arca2010 ER - TY - JOUR AU - Kharebava, G. AU - Makonchuk, D. AU - Kalita, K. B. AU - Zheng, J. J. AU - Hetman, M. PY - 2008 DA - 2008// TI - Requirement of 3-phosphoinositide-dependent protein kinase-1 for BDNF-mediated neuronal survival JO - J Neurosci VL - 28 UR - https://doi.org/10.1523/JNEUROSCI.2135-08.2008 DO - 10.1523/JNEUROSCI.2135-08.2008 ID - Kharebava2008 ER - TY - JOUR AU - Kwon, H. S. AU - Nakaya, N. AU - Abu-Asab, M. AU - Kim, H. S. AU - Tomarev, S. I. PY - 2014 DA - 2014// TI - Myocilin is involved in NgR1/Lingo-1-mediated oligodendrocyte differentiation and myelination of the optic nerve JO - J Neurosci VL - 34 UR - https://doi.org/10.1523/JNEUROSCI.4731-13.2014 DO - 10.1523/JNEUROSCI.4731-13.2014 ID - Kwon2014 ER - TY - JOUR AU - Meyer, R. C. AU - Giddens, M. M. AU - Coleman, B. M. AU - Hall, R. A. PY - 2014 DA - 2014// TI - The protective role of prosaposin and its receptors in the nervous system JO - Brain Res VL - 1585 UR - https://doi.org/10.1016/j.brainres.2014.08.022 DO - 10.1016/j.brainres.2014.08.022 ID - Meyer2014 ER - TY - JOUR AU - Zhou, J. AU - Liu, Q. AU - Mao, M. AU - Tong, Y. PY - 2014 DA - 2014// TI - Huwe1 as a therapeutic target for neural injury JO - Genet Mol Res VL - 13 UR - https://doi.org/10.4238/2014.June.9.18 DO - 10.4238/2014.June.9.18 ID - Zhou2014 ER - TY - JOUR AU - Zurashvili, T. AU - Cordon-Barris, L. AU - Ruiz-Babot, G. AU - Zhou, X. AU - Lizcano, J. M. AU - Gomez, N. AU - Gimenez-Llort, L. AU - Bayascas, J. R. PY - 2013 DA - 2013// TI - Interaction of PDK1 with phosphoinositides is essential for neuronal differentiation but dispensable for neuronal survival JO - Mol Cell Biol VL - 33 UR - https://doi.org/10.1128/MCB.01052-12 DO - 10.1128/MCB.01052-12 ID - Zurashvili2013 ER - TY - JOUR AU - Cho, Y. AU - Cavalli, V. PY - 2012 DA - 2012// TI - HDAC5 is a novel injury-regulated tubulin deacetylase controlling axon regeneration JO - EMBO J VL - 31 UR - https://doi.org/10.1038/emboj.2012.160 DO - 10.1038/emboj.2012.160 ID - Cho2012 ER - TY - JOUR AU - Cho, Y. AU - Sloutsky, R. AU - Naegle, K. M. AU - Cavalli, V. PY - 2013 DA - 2013// TI - Injury-induced HDAC5 nuclear export is essential for axon regeneration JO - Cell VL - 155 UR - https://doi.org/10.1016/j.cell.2013.10.004 DO - 10.1016/j.cell.2013.10.004 ID - Cho2013 ER - TY - JOUR AU - Benedek, G. AU - Chaudhary, P. AU - Meza-Romero, R. AU - Calkins, E. AU - Kent, G. AU - Offner, H. AU - Bourdette, D. AU - Vandenbark, A. A. PY - 2017 DA - 2017// TI - Sex-dependent treatment of chronic EAE with partial MHC class II constructs JO - J Neuroinflammation VL - 14 UR - https://doi.org/10.1186/s12974-017-0873-y DO - 10.1186/s12974-017-0873-y ID - Benedek2017 ER - TY - JOUR AU - Kipp, M. AU - Amor, S. AU - Krauth, R. AU - Beyer, C. PY - 2012 DA - 2012// TI - Multiple sclerosis: neuroprotective alliance of estrogen-progesterone and gender JO - Front Neuroendocrinol VL - 33 UR - https://doi.org/10.1016/j.yfrne.2012.01.001 DO - 10.1016/j.yfrne.2012.01.001 ID - Kipp2012 ER - TY - JOUR AU - Kovats, S. PY - 2015 DA - 2015// TI - Estrogen receptors regulate innate immune cells and signaling pathways JO - Cell Immunol VL - 294 UR - https://doi.org/10.1016/j.cellimm.2015.01.018 DO - 10.1016/j.cellimm.2015.01.018 ID - Kovats2015 ER - TY - JOUR AU - Polanczyk, M. J. AU - Hopke, C. AU - Vandenbark, A. A. AU - Offner, H. PY - 2006 DA - 2006// TI - Estrogen-mediated immunomodulation involves reduced activation of effector T cells, potentiation of Treg cells, and enhanced expression of the PD-1 costimulatory pathway JO - J Neurosci Res VL - 84 UR - https://doi.org/10.1002/jnr.20881 DO - 10.1002/jnr.20881 ID - Polanczyk2006 ER - TY - JOUR AU - Donnan, G. A. AU - Fisher, M. AU - Macleod, M. AU - Davis, S. M. PY - 2008 DA - 2008// TI - Stroke JO - Lancet VL - 371 UR - https://doi.org/10.1016/S0140-6736(08)60694-7 DO - 10.1016/S0140-6736(08)60694-7 ID - Donnan2008 ER - TY - JOUR AU - Lindsay, P. AU - Furie, K. L. AU - Davis, S. M. AU - Donnan, G. A. AU - Norrving, B. PY - 2014 DA - 2014// TI - World stroke organization global stroke services guidelines and action plan JO - Int J Stroke VL - 9 Suppl A100 UR - https://doi.org/10.1111/ijs.12371 DO - 10.1111/ijs.12371 ID - Lindsay2014 ER - TY - JOUR AU - Ovbiagele, B. AU - Goldstein, L. B. AU - Higashida, R. T. AU - Howard, V. J. AU - Johnston, S. C. AU - Khavjou, O. A. AU - Lackland, D. T. AU - Lichtman, J. H. AU - Mohl, S. AU - Sacco, R. L. PY - 2013 DA - 2013// TI - Forecasting the future of stroke in the United States: a policy statement from the American Heart Association and American Stroke Association JO - Stroke VL - 44 UR - https://doi.org/10.1161/STR.0b013e31829734f2 DO - 10.1161/STR.0b013e31829734f2 ID - Ovbiagele2013 ER - TY - JOUR AU - Campanella, M. AU - Sciorati, C. AU - Tarozzo, G. AU - Beltramo, M. PY - 2002 DA - 2002// TI - Flow cytometric analysis of inflammatory cells in ischemic rat brain JO - Stroke VL - 33 UR - https://doi.org/10.1161/hs0202.103399 DO - 10.1161/hs0202.103399 ID - Campanella2002 ER - TY - JOUR AU - Chamorro, A. AU - Meisel, A. AU - Planas, A. M. AU - Urra, X. AU - Beek, D. AU - Veltkamp, R. PY - 2012 DA - 2012// TI - The immunology of acute stroke JO - Nat Rev Neurol VL - 8 UR - https://doi.org/10.1038/nrneurol.2012.98 DO - 10.1038/nrneurol.2012.98 ID - Chamorro2012 ER - TY - JOUR AU - Offner, H. AU - Subramanian, S. AU - Parker, S. M. AU - Afentoulis, M. E. AU - Vandenbark, A. A. AU - Hurn, P. D. PY - 2006 DA - 2006// TI - Experimental stroke induces massive, rapid activation of the peripheral immune system JO - J Cereb Blood Flow Metab VL - 26 UR - https://doi.org/10.1038/sj.jcbfm.9600217 DO - 10.1038/sj.jcbfm.9600217 ID - Offner2006 ER - TY - JOUR AU - Pennypacker, K. R. AU - Offner, H. PY - 2015 DA - 2015// TI - The role of the spleen in ischemic stroke JO - J Cereb Blood Flow Metab VL - 35 UR - https://doi.org/10.1038/jcbfm.2014.212 DO - 10.1038/jcbfm.2014.212 ID - Pennypacker2015 ER - TY - JOUR AU - Urra, X. AU - Cervera, A. AU - Obach, V. AU - Climent, N. AU - Planas, A. M. AU - Chamorro, A. PY - 2009 DA - 2009// TI - Monocytes are major players in the prognosis and risk of infection after acute stroke JO - Stroke VL - 40 UR - https://doi.org/10.1161/STROKEAHA.108.532085 DO - 10.1161/STROKEAHA.108.532085 ID - Urra2009 ER - TY - JOUR AU - Elkind, M. S. AU - Cheng, J. AU - Rundek, T. AU - Boden-Albala, B. AU - Sacco, R. L. PY - 2004 DA - 2004// TI - Leukocyte count predicts outcome after ischemic stroke: the Northern Manhattan Stroke Study JO - J Stroke Cerebrovasc Dis VL - 13 UR - https://doi.org/10.1016/j.jstrokecerebrovasdis.2004.07.004 DO - 10.1016/j.jstrokecerebrovasdis.2004.07.004 ID - Elkind2004 ER - TY - JOUR AU - Offner, H. AU - Subramanian, S. AU - Parker, S. M. AU - Wang, C. AU - Afentoulis, M. E. AU - Lewis, A. AU - Vandenbark, A. A. AU - Hurn, P. D. PY - 2006 DA - 2006// TI - Splenic atrophy in experimental stroke is accompanied by increased regulatory T cells and circulating macrophages JO - J Immunol VL - 176 UR - https://doi.org/10.4049/jimmunol.176.11.6523 DO - 10.4049/jimmunol.176.11.6523 ID - Offner2006 ER - TY - JOUR AU - Offner, H. AU - Vandenbark, A. A. AU - Hurn, P. D. PY - 2009 DA - 2009// TI - Effect of experimental stroke on peripheral immunity: CNS ischemia induces profound immunosuppression JO - Neuroscience VL - 158 UR - https://doi.org/10.1016/j.neuroscience.2008.05.033 DO - 10.1016/j.neuroscience.2008.05.033 ID - Offner2009 ER - TY - JOUR AU - Seifert, H. A. AU - Hall, A. A. AU - Chapman, C. B. AU - Collier, L. A. AU - Willing, A. E. AU - Pennypacker, K. R. PY - 2012 DA - 2012// TI - A transient decrease in spleen size following stroke corresponds to splenocyte release into systemic circulation JO - J NeuroImmune Pharmacol VL - 7 UR - https://doi.org/10.1007/s11481-012-9406-8 DO - 10.1007/s11481-012-9406-8 ID - Seifert2012 ER - TY - JOUR AU - Ren, X. AU - Akiyoshi, K. AU - Grafe, M. R. AU - Vandenbark, A. A. AU - Hurn, P. D. AU - Herson, P. S. AU - Offner, H. PY - 2012 DA - 2012// TI - Myelin specific cells infiltrate MCAO lesions and exacerbate stroke severity JO - Metab Brain Dis VL - 27 UR - https://doi.org/10.1007/s11011-011-9267-5 DO - 10.1007/s11011-011-9267-5 ID - Ren2012 ER - TY - JOUR AU - Gordon, S. PY - 2003 DA - 2003// TI - Alternative activation of macrophages JO - Nat Rev Immunol VL - 3 UR - https://doi.org/10.1038/nri978 DO - 10.1038/nri978 ID - Gordon2003 ER - TY - JOUR AU - Albers, G. W. AU - Bates, V. E. AU - Clark, W. M. AU - Bell, R. AU - Verro, P. AU - Hamilton, S. A. PY - 2000 DA - 2000// TI - Intravenous tissue-type plasminogen activator for treatment of acute stroke: the Standard Treatment with Alteplase to Reverse Stroke (STARS) study JO - JAMA VL - 283 UR - https://doi.org/10.1001/jama.283.9.1145 DO - 10.1001/jama.283.9.1145 ID - Albers2000 ER - TY - STD TI - Benedek G, Vandenbark AA, Alkayed NJ, Offner H. Partial MHC class II constructs as novel immunomodulatory therapy for stroke. Neurochem Int. 2017;107:138–47. ID - ref59 ER - TY - JOUR AU - Bix, G. J. AU - Fraser, J. F. AU - Mack, W. J. AU - Carmichael, S. T. AU - Perez-Pinzon, M. AU - Offner, H. AU - Sansing, L. AU - Bosetti, F. AU - Ayata, C. AU - Pennypacker, K. R. PY - 2018 DA - 2018// TI - Uncovering the Rosetta stone: report from the first annual conference on key elements in translating stroke therapeutics from pre-clinical to clinical JO - Transl Stroke Res VL - 9 UR - https://doi.org/10.1007/s12975-018-0628-9 DO - 10.1007/s12975-018-0628-9 ID - Bix2018 ER - TY - JOUR AU - Yang, L. AU - Kong, Y. AU - Ren, H. AU - Li, M. AU - Wei, C. J. AU - Shi, E. AU - Jin, W. N. AU - Hao, J. AU - Vandenbark, A. A. AU - Offner, H. PY - 2017 DA - 2017// TI - Upregulation of CD74 and its potential association with disease severity in subjects with ischemic stroke JO - Neurochem Int VL - 107 UR - https://doi.org/10.1016/j.neuint.2016.11.007 DO - 10.1016/j.neuint.2016.11.007 ID - Yang2017 ER - TY - JOUR AU - Benedek, G. AU - Meza-Romero, R. AU - Andrew, S. AU - Leng, L. AU - Burrows, G. G. AU - Bourdette, D. AU - Offner, H. AU - Bucala, R. AU - Vandenbark, A. A. PY - 2013 DA - 2013// TI - Partial MHC class II constructs inhibit MIF/CD74 binding and downstream effects JO - Eur J Immunol VL - 43 UR - https://doi.org/10.1002/eji.201243162 DO - 10.1002/eji.201243162 ID - Benedek2013 ER - TY - STD TI - Pan J, Palmateer J, Schallert T, Hart M, Pandya A, Vandenbark AA, Offner H, Hurn PD. Novel humanized recombinant T cell receptor ligands protect the female brain after experimental stroke. Transl Stroke Res. 2014;5:577–85. ID - ref63 ER - TY - JOUR AU - Brown, C. M. AU - Bushnell, C. D. AU - Samsa, G. P. AU - Goldstein, L. B. AU - Colton, C. A. PY - 2015 DA - 2015// TI - Chronic systemic immune dysfunction in African-Americans with small vessel-type ischemic stroke JO - Transl Stroke Res VL - 6 UR - https://doi.org/10.1007/s12975-015-0424-8 DO - 10.1007/s12975-015-0424-8 ID - Brown2015 ER - TY - JOUR AU - Chen, S. AU - Yang, Q. AU - Chen, G. AU - Zhang, J. H. PY - 2015 DA - 2015// TI - An update on inflammation in the acute phase of intracerebral hemorrhage JO - Transl Stroke Res VL - 6 UR - https://doi.org/10.1007/s12975-014-0384-4 DO - 10.1007/s12975-014-0384-4 ID - Chen2015 ER - TY - JOUR AU - An, C. AU - Shi, Y. AU - Li, P. AU - Hu, X. AU - Gan, Y. AU - Stetler, R. A. AU - Leak, R. K. AU - Gao, Y. AU - Sun, B. L. AU - Zheng, P. AU - Chen, J. PY - 2014 DA - 2014// TI - Molecular dialogs between the ischemic brain and the peripheral immune system: dualistic roles in injury and repair JO - Prog Neurobiol VL - 115 UR - https://doi.org/10.1016/j.pneurobio.2013.12.002 DO - 10.1016/j.pneurobio.2013.12.002 ID - An2014 ER - TY - JOUR AU - Liesz, A. AU - Kleinschnitz, C. PY - 2016 DA - 2016// TI - Regulatory T cells in post-stroke immune homeostasis JO - Transl Stroke Res VL - 7 UR - https://doi.org/10.1007/s12975-016-0465-7 DO - 10.1007/s12975-016-0465-7 ID - Liesz2016 ER - TY - JOUR AU - Atangana, E. AU - Schneider, U. C. AU - Blecharz, K. AU - Magrini, S. AU - Wagner, J. AU - Nieminen-Kelha, M. AU - Kremenetskaia, I. AU - Heppner, F. L. AU - Engelhardt, B. AU - Vajkoczy, P. PY - 2017 DA - 2017// TI - Intravascular inflammation triggers intracerebral activated microglia and contributes to secondary brain injury after experimental subarachnoid hemorrhage (eSAH) JO - Transl Stroke Res VL - 8 UR - https://doi.org/10.1007/s12975-016-0485-3 DO - 10.1007/s12975-016-0485-3 ID - Atangana2017 ER - TY - JOUR AU - Petrone, A. B. AU - O'Connell, G. C. AU - Regier, M. D. AU - Chantler, P. D. AU - Simpkins, J. W. AU - Barr, T. L. PY - 2016 DA - 2016// TI - The role of arginase 1 in post-stroke immunosuppression and ischemic stroke severity JO - Transl Stroke Res VL - 7 UR - https://doi.org/10.1007/s12975-015-0431-9 DO - 10.1007/s12975-015-0431-9 ID - Petrone2016 ER - TY - JOUR AU - Yang, B. AU - Parsha, K. AU - Schaar, K. AU - Xi, X. AU - Aronowski, J. AU - Savitz, S. I. PY - 2016 DA - 2016// TI - Various cell populations within the mononuclear fraction of bone marrow contribute to the beneficial effects of autologous bone marrow cell therapy in a rodent stroke model JO - Transl Stroke Res VL - 7 UR - https://doi.org/10.1007/s12975-016-0462-x DO - 10.1007/s12975-016-0462-x ID - Yang2016 ER - TY - STD TI - Wang J, Ye Q, Xu J, Benedek G, Zhang H, Yang Y, Liu H, Meza-Romero R, Vandenbark AA, Offner H, Gao Y. DRalpha1-MOG-35-55 Reduces Permanent Ischemic Brain Injury. Transl Stroke Res. 2017;8:284–93. ID - ref71 ER - TY - JOUR AU - Benedek, G. AU - Zhu, W. AU - Libal, N. AU - Casper, A. AU - Yu, X. AU - Meza-Romero, R. AU - Vandenbark, A. A. AU - Alkayed, N. J. AU - Offner, H. PY - 2014 DA - 2014// TI - A novel HLA-DRalpha1-MOG-35-55 construct treats experimental stroke JO - Metab Brain Dis VL - 29 UR - https://doi.org/10.1007/s11011-013-9440-0 DO - 10.1007/s11011-013-9440-0 ID - Benedek2014 ER - TY - JOUR AU - Scott, J. C. AU - Woods, S. P. AU - Matt, G. E. AU - Meyer, R. A. AU - Heaton, R. K. AU - Atkinson, J. H. AU - Grant, I. PY - 2007 DA - 2007// TI - Neurocognitive effects of methamphetamine: a critical review and meta-analysis JO - Neuropsychol Rev VL - 17 UR - https://doi.org/10.1007/s11065-007-9031-0 DO - 10.1007/s11065-007-9031-0 ID - Scott2007 ER - TY - JOUR AU - Hoffman, W. F. AU - Moore, M. AU - Templin, R. AU - McFarland, B. AU - Hitzemann, R. J. AU - Mitchell, S. H. PY - 2006 DA - 2006// TI - Neuropsychological function and delay discounting in methamphetamine-dependent individuals JO - Psychopharmacology VL - 188 UR - https://doi.org/10.1007/s00213-006-0494-0 DO - 10.1007/s00213-006-0494-0 ID - Hoffman2006 ER - TY - JOUR AU - McLellan, A. T. AU - Lewis, D. C. AU - O'Brien, C. P. AU - Kleber, H. D. PY - 2000 DA - 2000// TI - Drug dependence, a chronic medical illness: implications for treatment, insurance, and outcomes evaluation JO - JAMA VL - 284 UR - https://doi.org/10.1001/jama.284.13.1689 DO - 10.1001/jama.284.13.1689 ID - McLellan2000 ER - TY - JOUR AU - London, E. D. AU - Simon, S. L. AU - Berman, S. M. AU - Mandelkern, M. A. AU - Lichtman, A. M. AU - Bramen, J. AU - Shinn, A. K. AU - Miotto, K. AU - Learn, J. AU - Dong, Y. PY - 2004 DA - 2004// TI - Mood disturbances and regional cerebral metabolic abnormalities in recently abstinent methamphetamine abusers JO - Arch Gen Psychiatry VL - 61 UR - https://doi.org/10.1001/archpsyc.61.1.73 DO - 10.1001/archpsyc.61.1.73 ID - London2004 ER - TY - JOUR AU - Schwartz, D. L. AU - Mitchell, A. D. AU - Lahna, D. L. AU - Luber, H. S. AU - Huckans, M. S. AU - Mitchell, S. H. AU - Hoffman, W. F. PY - 2010 DA - 2010// TI - Global and local morphometric differences in recently abstinent methamphetamine-dependent individuals JO - Neuroimage VL - 50 UR - https://doi.org/10.1016/j.neuroimage.2010.01.056 DO - 10.1016/j.neuroimage.2010.01.056 ID - Schwartz2010 ER - TY - JOUR AU - Berman, S. AU - O'Neill, J. AU - Fears, S. AU - Bartzokis, G. AU - London, E. D. PY - 2008 DA - 2008// TI - Abuse of amphetamines and structural abnormalities in the brain JO - Ann N Y Acad Sci VL - 1141 UR - https://doi.org/10.1196/annals.1441.031 DO - 10.1196/annals.1441.031 ID - Berman2008 ER - TY - JOUR AU - Hoffman, W. F. AU - Schwartz, D. L. AU - Huckans, M. S. AU - McFarland, B. H. AU - Meiri, G. AU - Stevens, A. A. AU - Mitchell, S. H. PY - 2008 DA - 2008// TI - Cortical activation during delay discounting in abstinent methamphetamine dependent individuals JO - Psychopharmacology VL - 201 UR - https://doi.org/10.1007/s00213-008-1261-1 DO - 10.1007/s00213-008-1261-1 ID - Hoffman2008 ER - TY - JOUR AU - Shah, A. AU - Silverstein, P. S. AU - Singh, D. P. AU - Kumar, A. PY - 2012 DA - 2012// TI - Involvement of metabotropic glutamate receptor 5, AKT/PI3K signaling and NF-kappaB pathway in methamphetamine-mediated increase in IL-6 and IL-8 expression in astrocytes JO - J Neuroinflammation VL - 9 UR - https://doi.org/10.1186/1742-2094-9-52 DO - 10.1186/1742-2094-9-52 ID - Shah2012 ER - TY - JOUR AU - In, S. W. AU - Son, E. W. AU - Rhee, D. K. AU - Pyo, S. PY - 2005 DA - 2005// TI - Methamphetamine administration produces immunomodulation in mice JO - J Toxicol Environ Health A VL - 68 UR - https://doi.org/10.1080/15287390500177156 DO - 10.1080/15287390500177156 ID - In2005 ER - TY - JOUR AU - Loftis, J. M. AU - Wilhelm, C. J. AU - Vandenbark, A. A. AU - Huckans, M. PY - 2013 DA - 2013// TI - Partial MHC/neuroantigen peptide constructs: a potential neuroimmune-based treatment for methamphetamine addiction JO - PLoS One VL - 8 UR - https://doi.org/10.1371/journal.pone.0056306 DO - 10.1371/journal.pone.0056306 ID - Loftis2013 ER - TY - JOUR AU - McKee, C. A. AU - Lukens, J. R. PY - 2016 DA - 2016// TI - Emerging roles for the immune system in traumatic brain injury JO - Front Immunol VL - 7 UR - https://doi.org/10.3389/fimmu.2016.00556 DO - 10.3389/fimmu.2016.00556 ID - McKee2016 ER - TY - JOUR AU - Kumar, A. AU - Loane, D. J. PY - 2012 DA - 2012// TI - Neuroinflammation after traumatic brain injury: opportunities for therapeutic intervention JO - Brain Behav Immun VL - 26 UR - https://doi.org/10.1016/j.bbi.2012.06.008 DO - 10.1016/j.bbi.2012.06.008 ID - Kumar2012 ER - TY - JOUR AU - Raghupathi, R. PY - 2004 DA - 2004// TI - Cell death mechanisms following traumatic brain injury JO - Brain Pathol VL - 14 UR - https://doi.org/10.1111/j.1750-3639.2004.tb00056.x DO - 10.1111/j.1750-3639.2004.tb00056.x ID - Raghupathi2004 ER - TY - JOUR AU - Ramlackhansingh, A. F. AU - Brooks, D. J. AU - Greenwood, R. J. AU - Bose, S. K. AU - Turkheimer, F. E. AU - Kinnunen, K. M. AU - Gentleman, S. AU - Heckemann, R. A. AU - Gunanayagam, K. AU - Gelosa, G. AU - Sharp, D. J. PY - 2011 DA - 2011// TI - Inflammation after trauma: microglial activation and traumatic brain injury JO - Ann Neurol VL - 70 UR - https://doi.org/10.1002/ana.22455 DO - 10.1002/ana.22455 ID - Ramlackhansingh2011 ER - TY - JOUR AU - Yang, L. AU - Liu, Z. AU - Ren, H. AU - Zhang, L. AU - Gao, S. AU - Ren, L. AU - Chai, Z. AU - Meza-Romero, R. AU - Benedek, G. AU - Vandenbark, A. A. PY - 2017 DA - 2017// TI - DRalpha1-MOG-35-55 treatment reduces lesion volumes and improves neurological deficits after traumatic brain injury JO - Metab Brain Dis VL - 32 UR - https://doi.org/10.1007/s11011-017-9991-6 DO - 10.1007/s11011-017-9991-6 ID - Yang2017 ER - TY - STD TI - Meza-Romero R, Benedek G, Gerstner G, Kent G, Nguyen H, Offner H, Vandenbark AA. Increased CD74 binding and EAE treatment efficacy of a modified DRa1 molecular construct. Metab Brain Dis. 2018; In Press. ID - ref88 ER -