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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: The phagocytic state of brain myeloid cells after ischemia revealed by superresolution structured illumination microscopy

Fig. 5

Transmission electron microscopy (TEM) images of macrophages at 48 h and 7 days after pMCAo. TEM showing a macrophage in the ischemic area at 48 h (a) or 7 days (b) after pMCAo. Scale bar = 2 μm. The macrophage at 48 h had primary lysosomes clustered close to the cell membrane (see the magnificated insert, a, scale bar = 0.5 μm), while at 7 days it was over-loaded of lysosomes at different maturation stages positioned further from cell membrane (see the magnificated insert, b, scale bar = 0.5 μm). At 48 h, 74% of total lysosomes were at < 700 nm from the cell membrane, while at 7 days, only the 57% of lysosomes were at this distance (c)

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