Table 3 Biomarker concentrations in athletes with SRC and healthy athletes in the subacute period
From: Evidence of a distinct peripheral inflammatory profile in sport-related concussion
Biomarker | Healthy male (n = 43) | SRC male (n = 21) | Healthy female (n = 44) | SRC female (n = 22) | P value | FDR |
|---|---|---|---|---|---|---|
IFN-γ | 3.5 (2.8–5.2) | 3.4 (2.6–5.5) | 3.9 (2.9–7.8) | 3.7 (2.6–4.8) | 0.32 | No |
TNF-α | 1.7 (1.4–2.0) | 1.7 (1.4–2.1) | 1.5 (1.3–2.0) | 1.5 (1.2–1.9) | 0.83 | No |
MPO (ng/mL) | 11.2 (8.1–15.8) | 12.3 (7.7–20.2) | 7.9 (5.8–11.1) | 9.0 (7.5–12.2) | 0.63 | No |
IL-8 | 1.9 (1.6–2.5) | 2.0 (1.7–2.4) | 1.6 (1.1–2.2) | 1.8 (1.0–2.3) | 0.69 | No |
Eotaxin | 85.5 (75.1–106.6) | 95.4 (83.4–126.7) | 73.3 (63.3–89.3) | 81.0 (64.5–93.4) | 0.07 | No |
IP-10 | 159.2 (129.1–226.5) | 181.5 (136.1–220.1) | 156.1 (132.5–251.2) | 207.7 (165.3–288.9) | 0.13 | No |
MCP-1 | 68.9 (58.8–77.7) | 66.9 (57.7–75.6) | 58.7 (50.9–69.0) | 53.3 (44.2–63.7) | 0.25 | No |
MCP-4 | 20.8 (16.3–25.5) | 26.5 (20.5–32.1) | 19.0 (16.8–22.4) | 21.2 (18.5–27.7) | 0.00 | Yes |
MIP-1β | 29.2 (25.9–40.3) | 42.1 (31.4–53.6) | 27.7 (22.2–33.6) | 31.8 (26.0–39.4) | 0.00 | Yes |
TARC | 50.0 (38.9–75.2) | 71.3 (44.8–94.6) | 42.7 (32.7–54.6) | 54.0 (37.5–67.5) | 0.02 | No |