Table 5 Biomarker concentrations in athletes with MSK injury and healthy athletes at medical clearance
From: Evidence of a distinct peripheral inflammatory profile in sport-related concussion
Biomarker | Healthy male (n = 43) | SRC male (n = 14) | Healthy female (n = 44) | SRC female (n = 18) | P value | FDR |
|---|---|---|---|---|---|---|
IFN-γ | 3.5 (2.8–5.2) | 2.9 (2.5–4.3) | 3.9 (2.9–7.8) | 2.9 (2.3–4.2) | 0.02 | No |
TNF-α | 1.7 (1.4–2.0) | 1.5 (1.2–1.8) | 1.5 (1.3–2.0) | 1.6 (1.2–2.1) | 0.48 | No |
MPO (ng/mL) | 11.2 (8.1–15.8) | 9.0 (5.7–15.2) | 7.9 (5.8–11.1) | 7.6 (6.0–12.4) | 0.34 | No |
IL-8 | 1.9 (1.6–2.5) | 2.4 (1.5–2.7) | 1.6 (1.1–2.2) | 1.6 (1.2–1.9) | 0.92 | No |
Eotaxin | 85.5 (75.1–106.6) | 91.5 (77.4–99.5) | 73.3 (63.3–89.3) | 87.7 (71.2–95.7) | 0.12 | No |
IP-10 | 159.2 (129.1–226.5) | 177.7 (140.0–201.0) | 156.1 (132.5–251.2) | 187.2 (145.6–233.3) | 0.38 | No |
MCP-1 | 68.9 (58.8–77.7) | 70.1 (61.0–84.0) | 58.7 (50.9–69.0) | 57.5 (54.4–78.5) | 0.48 | No |
MCP-4 | 20.8 (16.3–25.5) | 25.2 (23.4–27.1) | 19.0 (16.8–22.4) | 20.0 (17.8–36.0) | 0.00 | No |
MIP-1β | 29.2 (25.9–40.3) | 41.3 (36.5–45.0) | 27.7 (22.2–33.6) | 32.0 (25.0–40.9) | 0.01 | No |
TARC | 50.0 (38.9–75.2) | 54.3 (45.6–67.3) | 42.7 (32.7–54.6) | 46.9 (39.1–56.3) | 0.24 | No |