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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: The TRPC6 inhibitor, larixyl acetate, is effective in protecting against traumatic brain injury-induced systemic endothelial dysfunction

Fig. 2

Effect of TBI on reactivity and endothelial function in mouse aortic arches from C57BL/6. a, d, and g Bar graphs comparing the active tensions in C57BL/6 aortic arch rings, respectively, in the presence of 70 mM KCl in sham and TBI mice after 1, 7, and 21 days. b, e, and h Concentration-response relationships for phenylephrine (PE)-induced contractions in aortic arch rings from sham and TBI C57BL/6 mice after 1, 7, and 21 days. c, f, and i Concentration-response relationships for acetylcholine-induced dilation in phenylephrine-precontracted rings from sham and TBI C57BL/6 mice. The insets show the sample traces of active tension changes in aortas from sham (black lines) and TBI (red lines) mice. PE - phenylephrine, ACh - acetylcholine

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