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Fig. 7 | Journal of Neuroinflammation

Fig. 7

From: The TRPC6 inhibitor, larixyl acetate, is effective in protecting against traumatic brain injury-induced systemic endothelial dysfunction

Fig. 7

One hour in vitro pre-treatment with LPS induced endothelial dysfunction in 129S-C57BL/6-F2 but not in 129S-C57BL/6-TRPC6 knockout mouse aortic arch rings. a The LPS effect in wild type 129S-C57BL/6-F2 mouse aortic arch rings. Sample traces are shown. LPS was added at the time indicated by the arrow in the beginning of the right trace. b Summary for the data in a. c, d Sample traces and a summary for the data obtained in aortic arch rings isolated from 129S-C57BL/6-TRPC6 knockout mice. PE - phenylephrine, ACh - acetylcholine, LPS - lipopolysaccharide

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