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Table 1 Mating combinations. Four pairs in each group were successfully time mated, totalling 16 pairs. Each pair produces WT and Map2k7 Hz embryos

From: JNK signalling mediates aspects of maternal immune activation: importance of maternal genotype in relation to schizophrenia risk

Breeding Treatment Maternal plasma samples Litters Independent WT embryonic brain samples Independent Hz embryonic brain samples
Female WT ×
Male Map2k7 Hz
Saline (vehicle) 4 × WT 4 4 4
Female WT ×
Male Map2k7 Hz
PolyI:C
(20 mg/kg sc.)
4 × WT 4 4 4
Female Map2k7 Hz × Male WT Saline (vehicle) 4 × Hz 4 4 4
Female Map2k7 Hz × Male WT PolyI:C
(20 mg/kg sc.)
4 × Hz 4 4 4