Fig. 2

Gene expression of peripheral blood at 2 weeks and peripheral blood, spleen and brain at 12 weeks. a Gene expression of peripheral blood samples taken at 2 weeks post-transplant and tested for Il1b, Ccl2, Il6 and Tnfa (n = 6/group). b Gene expression of peripheral blood samples taken at 12 weeks post-transplant and tested for Il1b, Ccl2, Il6, and Tnfa (n = 6/group). c Spleen sample gene expression profiles were measured for the cytokines Il1b, Ccl2, Il6, Tnfa and Ifng. d Brain samples without a tumour were analysed for the cytokines Il1b, Ccl2, Il6 and Tnfa. Ccl2, Tnfa and Il6 expression in blood at 2 weeks, Il1b, Ccl2, Tnfa and Il6 expression in the blood at 12 weeks, Il6 expression in the spleen and Ccl2 expression in the brain failed Shapiro-Wilk normality test and were analysed using Kruskal-Wallis test with Dunn’s post hoc correction for multiple comparisons. All other samples were analysed using one-way ANOVA with Tukey’s post hoc correction for multiple comparisons. Error bar represents the SEM. ****p < 0.0001; ***p < 0.001; **p < 0.01; *p < 0.05. Samples with ≥ 5-fold difference in gene expression and unequal variance were log transformed (spleen; Tnfa, brain; Il1b, Ccl2 and Tnfa). Error bar represents the SEM. ****p < 0.0001; ***p < 0.001; **p < 0.01; *p < 0.05