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Fig. 7 | Journal of Neuroinflammation

Fig. 7

From: Oligodendrocyte-specific ATF4 inactivation does not influence the development of EAE

Fig. 7

ATF4 inactivation specifically in oligodendrocytes did not affect neuron loss in the CNS gray matter during EAE. ac NeuN IHC showed that ATF4 inactivation specifically in oligodendrocytes did not significantly change the number of lower motor neurons in the lumbar spinal cord of EAE mice at PID 21. df NeuN IHC showed that ATF4 inactivation specifically in oligodendrocytes did not significantly change the number of neurons in the layer V of the primary motor cortex in EAE mice at PID 21. gi Calbindin 2 IHC showed that ATF4 inactivation specifically in oligodendrocytes did not significantly change the number of Purkinje neurons in the cerebellum of EAE mice at PID 21. Scale bars: a, b, d, e, g, h, 50 μm. N = 4 animals. Error bars represent SD, n.s. not significant

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