Skip to main content
Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Co-inhibition of PGF and VEGF blocks their expression in mononuclear phagocytes and limits neovascularization and leakage in the murine retina

Fig. 1

Effects of PGF and VEGF inhibition on vascular leakage in fundus fluorescein angiography. a Representative fundus fluorescein angiography images of animals of the indicated treatment groups 3 and 7 days after laser-induced damage. b Quantification of vascular leakage by analyzing pixel intensities 3 days after laser-induced damage (n = 13 eyes for IgG, n = 14 eyes for aVEGF, n = 13 eyes for aPGF, n = 20 eyes for aVEGF/aPGF, n = 13 eyes for aflibercept). c Quantification of vascular leakage by analyzing pixel intensities 7 days after laser-induced damage (n = 26 eyes for IgG, n = 14 eyes for aVEGF, n = 14 eyes for aPGF, n = 16 eyes for aVEGF/aPGF, n = 27 eyes for aflibercept). d Quantification of vascular leakage area 3 days after laser-induced damage (n = 13 eyes for IgG, n = 14 eyes for aVEGF, n = 13 eyes for aPGF, n = 20 eyes for aVEGF/aPGF, n = 13 eyes for aflibercept). e Quantification of vascular leakage area 7 days after laser-induced damage (n = 26 eyes for IgG, n = 14 eyes for aVEGF, n = 14 eyes for aPGF, n = 16 eyes for aVEGF/aPGF, n = 27 eyes for aflibercept). Data are shown as mean ± SEM (*P < 0.05, **P < 0.01, ***P < 0.001)

Back to article page