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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Semaphorin4A causes loss of mature oligodendrocytes and demyelination in vivo

Fig. 1

Elevated levels of Sema4A in the CSF of HIV-infected individuals. a CSF from HIV+ individuals displays a significantly higher level of Sema4A levels (53.72 ± 14.37 ng/mL, n = 50) relative to HIV-negative, non-demyelinated control patients (7.22 ± 2.28 ng/mL, n = 19). b Serum values of Sema4A from HIV+ individuals (401.92 ± 81.73 ng/mL, n = 50) is significantly elevated relative to HIV-negative, non-demyelinated control patients (12.38 ± 9.78 ng/mL, n = 10). Though the data are the same, scatterplot lines represent mean values, whereas the box and whisker plots represent the medians and interquartile ranges. Statistical significance was evaluated using the Mann-Whitney test; ***p < 0.0001

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