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Table 1 Baseline characteristics of 3124 acute ischemic stroke patients according to white blood cell and blood glucose level

From: Combined utility of white blood cell count and blood glucose for predicting in-hospital outcomes in acute ischemic stroke

Characteristicsa

NWNG

NWHG

HWNG

HWHG

P value

Number of subjects

2025

681

266

152

 

Demographics

 Age, years

68.8 ± 12.8

68.8 ± 11.4

66.5 ± 16.3

67.6 ± 14.3

0.031

 Male sex

1181 (58.3)

356 (52.3)

170 (63.9)

93 (61.2)

0.004

 Cigarette smoking status

420 (20.7)

119 (17.5)

54 (20.3)

25 (16.4)

0.206

 Alcohol consumption

205 (10.1)

62 (9.1)

21 (7.9)

16 (10.5)

0.617

Clinical features

 Time from onset to hospital, hours

24.0 (6.0–72.0)

24.0 (5.0–72.0)

24.0 (4.0–48.0)

12.0 (3.0–48.0)

< 0.001

 Hospital stay, days

10.0 (8.0–13.0)

11.0 (8.0–15.0)

11.0 (7.0–15.0)

12.0 (7.5–19.0)

< 0.001

 Baseline systolic BP, mm Hg

151.0 ± 22.6

154.6 ± 22.0

153.4 ± 25.0

155.5 ± 22.6

0.001

 Baseline diastolic BP, mm Hg

85.1 ± 13.0

85.7 ± 12.5

87.1 ± 14.7

86.1 ± 14.6

0.087

 TG, mmol/L

1.2 (0.9–1.6)

1.4 (1.0–2.2)

1.1 (0.9–1.6)

1.2 (0.9–1.8)

< 0.001

 TC, mmol/L

4.5 (3.8–5.1)

4.7 (4.0–5.5)

4.6 (3.9–5.3)

4.9 (4.2–5.6)

< 0.001

 LDL-C, mmol/L

2.6 (2.1–3.2)

2.7 (2.1–3.4)

2.7 (2.2–3.2)

3.1 (2.3–3.7)

< 0.001

 HDL-C, mmol/L

1.2 (1.0–1.4)

1.2 (1.0–1.4)

1.2 (1.0–1.4)

1.2 (1.0–1.5)

0.079

 FG, mmol/L

5.3 (4.9–5.9)

8.9 (7.7–11.3)

5.6 (5.0–6.1)

9.2 (8.1–11.6)

< 0.001

 WBC, 103/uL

6.3 (5.2–7.5)

6.8 (5.6–8.0)

11.5 (10.6–13.0)

11.6 (10.6–13.7)

< 0.001

 eGFR, ml/min/1.73 m2

94.3 (76.2–114.8)

99.3 (78.2–124.6)

93.2 (71.2–117.2)

94.9 (64.3–115.8)

0.004

 Baseline NIHSS score

3.0 (2.0–6.0)

4.0 (2.0–7.0)

6.0 (3.0–12.0)

7.5 (3.5–15.0)

< 0.001

Medical history

 History of hypertension

1542 (76.1)

569 (83.6)

211 (79.3)

129 (84.9)

< 0.001

 History of diabetes mellitus

236 (11.7)

458 (67.3)

26 (9.8)

84 (55.3)

< 0.001

 History of coronary heart disease

97 (4.8)

48 (7.0)

15 (5.6)

14 (9.2)

0.029

 History of atrial fibrillation

283 (14.0)

108 (15.9)

56 (21.1)

30 (19.7)

0.007

 History of stroke

464 (22.9)

144 (21.1)

46 (17.3)

39 (25.7)

0.122

Medication history

 Antihypertensive therapy

1133 (56.0)

449 (65.9)

148 (55.6)

102 (67.1)

< 0.001

 Antiplatelet therapy

161 (8.0)

52 (7.6)

11 (4.1)

10 (6.6)

0.162

 Anticoagulation therapy

21 (1.0)

8 (1.2)

3 (1.1)

3 (2.0)

0.810

 Antiglycemic therapy

179 (8.8)

338 (49.6)

19 (7.1)

49 (32.2)

< 0.001

 Statin therapy

76 (3.8)

13 (1.9)

3 (1.1)

3 (2.0)

0.016

 Thrombolysis treatment

43 (2.1)

11 (1.6)

12 (4.5)

11 (7.2)

< 0.001

Stroke syndrome

< 0.001

 TACS

143 (7.1)

62 (9.1)

46 (17.3)

44 (28.9)

 

 PACS

1076 (53.1)

311 (45.7)

129 (48.5)

48 (31.6)

 

 POCS

416 (20.5)

209 (30.7)

70 (26.3)

48 (31.6)

 

 LACS

390 (19.3)

99 (14.5)

21 (7.9)

12 (7.9)

 
  1. aContinuous variables are expressed as mean ± standard deviation or as median (interquartile range). Categorical variables are expressed as frequency (percent)
  2. Abbreviations: BP blood pressure, TG triglycerides, TC total cholesterol, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, FG fasting glucose, eGFR estimated glomerular filtration rate, mRS modified Rankin Scale, NIHSS National Institutes of Health Stroke Scale, TACS total anterior circulation syndrome, PACS partial anterior circulation syndrome, POCS posterior circulation syndrome, LACS lacunar syndrome, Q quartile