Characteristicsa | NWNG | NWHG | HWNG | HWHG | P value |
---|---|---|---|---|---|
Number of subjects | 2025 | 681 | 266 | 152 | |
Demographics | |||||
Age, years | 68.8 ± 12.8 | 68.8 ± 11.4 | 66.5 ± 16.3 | 67.6 ± 14.3 | 0.031 |
Male sex | 1181 (58.3) | 356 (52.3) | 170 (63.9) | 93 (61.2) | 0.004 |
Cigarette smoking status | 420 (20.7) | 119 (17.5) | 54 (20.3) | 25 (16.4) | 0.206 |
Alcohol consumption | 205 (10.1) | 62 (9.1) | 21 (7.9) | 16 (10.5) | 0.617 |
Clinical features | |||||
Time from onset to hospital, hours | 24.0 (6.0–72.0) | 24.0 (5.0–72.0) | 24.0 (4.0–48.0) | 12.0 (3.0–48.0) | < 0.001 |
Hospital stay, days | 10.0 (8.0–13.0) | 11.0 (8.0–15.0) | 11.0 (7.0–15.0) | 12.0 (7.5–19.0) | < 0.001 |
Baseline systolic BP, mm Hg | 151.0 ± 22.6 | 154.6 ± 22.0 | 153.4 ± 25.0 | 155.5 ± 22.6 | 0.001 |
Baseline diastolic BP, mm Hg | 85.1 ± 13.0 | 85.7 ± 12.5 | 87.1 ± 14.7 | 86.1 ± 14.6 | 0.087 |
TG, mmol/L | 1.2 (0.9–1.6) | 1.4 (1.0–2.2) | 1.1 (0.9–1.6) | 1.2 (0.9–1.8) | < 0.001 |
TC, mmol/L | 4.5 (3.8–5.1) | 4.7 (4.0–5.5) | 4.6 (3.9–5.3) | 4.9 (4.2–5.6) | < 0.001 |
LDL-C, mmol/L | 2.6 (2.1–3.2) | 2.7 (2.1–3.4) | 2.7 (2.2–3.2) | 3.1 (2.3–3.7) | < 0.001 |
HDL-C, mmol/L | 1.2 (1.0–1.4) | 1.2 (1.0–1.4) | 1.2 (1.0–1.4) | 1.2 (1.0–1.5) | 0.079 |
FG, mmol/L | 5.3 (4.9–5.9) | 8.9 (7.7–11.3) | 5.6 (5.0–6.1) | 9.2 (8.1–11.6) | < 0.001 |
WBC, 103/uL | 6.3 (5.2–7.5) | 6.8 (5.6–8.0) | 11.5 (10.6–13.0) | 11.6 (10.6–13.7) | < 0.001 |
eGFR, ml/min/1.73 m2 | 94.3 (76.2–114.8) | 99.3 (78.2–124.6) | 93.2 (71.2–117.2) | 94.9 (64.3–115.8) | 0.004 |
Baseline NIHSS score | 3.0 (2.0–6.0) | 4.0 (2.0–7.0) | 6.0 (3.0–12.0) | 7.5 (3.5–15.0) | < 0.001 |
Medical history | |||||
History of hypertension | 1542 (76.1) | 569 (83.6) | 211 (79.3) | 129 (84.9) | < 0.001 |
History of diabetes mellitus | 236 (11.7) | 458 (67.3) | 26 (9.8) | 84 (55.3) | < 0.001 |
History of coronary heart disease | 97 (4.8) | 48 (7.0) | 15 (5.6) | 14 (9.2) | 0.029 |
History of atrial fibrillation | 283 (14.0) | 108 (15.9) | 56 (21.1) | 30 (19.7) | 0.007 |
History of stroke | 464 (22.9) | 144 (21.1) | 46 (17.3) | 39 (25.7) | 0.122 |
Medication history | |||||
Antihypertensive therapy | 1133 (56.0) | 449 (65.9) | 148 (55.6) | 102 (67.1) | < 0.001 |
Antiplatelet therapy | 161 (8.0) | 52 (7.6) | 11 (4.1) | 10 (6.6) | 0.162 |
Anticoagulation therapy | 21 (1.0) | 8 (1.2) | 3 (1.1) | 3 (2.0) | 0.810 |
Antiglycemic therapy | 179 (8.8) | 338 (49.6) | 19 (7.1) | 49 (32.2) | < 0.001 |
Statin therapy | 76 (3.8) | 13 (1.9) | 3 (1.1) | 3 (2.0) | 0.016 |
Thrombolysis treatment | 43 (2.1) | 11 (1.6) | 12 (4.5) | 11 (7.2) | < 0.001 |
Stroke syndrome | < 0.001 | ||||
TACS | 143 (7.1) | 62 (9.1) | 46 (17.3) | 44 (28.9) | |
PACS | 1076 (53.1) | 311 (45.7) | 129 (48.5) | 48 (31.6) | |
POCS | 416 (20.5) | 209 (30.7) | 70 (26.3) | 48 (31.6) | |
LACS | 390 (19.3) | 99 (14.5) | 21 (7.9) | 12 (7.9) |