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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: The agonistic TSPO ligand XBD173 attenuates the glial response thereby protecting inner retinal neurons in a murine model of retinal ischemia

Fig. 2

TSPO expression in the postischemic retina. a Retinal flatmounts labeled for TSPO focused on the ganglion cell and outer plexiform layer (GCL, OPL) at 3 and 14 dps. While in control retinae primarily endothelial cells and Müller cells appear to be positively labeled, TSPO-positive macrophages/microglia (arrowheads) show up in the postischemic retina irrespective of the treatment regimen. Scale bars, 20 μm. b Quantitative real-time PCR (qPCR) performed on retinal cell populations enriched via magnetic activated cell sorting. Bars represent mean values ± SEM (n = 3–6 mice of each treatment group and time point). */°/•P < 0.05. The color of the circle indicates the treatment group

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Journal of Neuroinflammation

ISSN: 1742-2094