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Fig. 7 | Journal of Neuroinflammation

Fig. 7

From: Activation of retinoid X receptor by bexarotene attenuates neuroinflammation via PPARγ/SIRT6/FoxO3a pathway after subarachnoid hemorrhage in rats

Fig. 7

RXR selective inhibitor UVI3003 reversed the anti-neuroinflammation effects of bexarotene and its regulation on downstream signaling proteins of PPARγ/SIRT6/p-FoxO3a at 24 h after SAH. a Representative western blot bands. bh Quantitative analyses of RXR, PPARγ, SIRT6, p-FoxO3a, IL-1β, IL-6, and TNF-α in the left hemisphere at 24 h after SAH. **P < 0.01 vs. sham, ##P < 0.01 vs. SAH + vehicle, and &&P < 0.01 vs. SAH + BEXA + vehicle. Error bars were represented as mean ± SD. n = 6 per group. Bexa bexarotene

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