Fig. 1

A dendrogram of the genes and their module assignments (a); a dendrogram of only the module eigengenes (representative of the overall gene expression within that module) (b). The significant modules in respect to Dx (cyan, darkolivegreen, greenyellow, magenta, red, sienna3, and tan) are marked with asterisks in (a) and colored in module-corresponding colors in (b). Dx-specific modules with significant overlap/enrichment with cell-specific genes are labeled in (a) with the specific cell type, and the hypergeometric probability p value of overlap between the module’s gene list and the cell type-specific gene list from Watkins et al. [31] and T cell-specific genes from Additional file 2: Table S1 from Chtanova et al. [32] is presented