Fig. 1
From: Impact of microbiota on central nervous system and neurological diseases: the gut-brain axis
Microbiota and the gut-brain axis. a The majority of microorganisms reside in the gastrointestinal tract of human beings and impact wide range of physiological or pathological activities of the host. b The concept of “gut-brain axis” includes complicated direct and indirect interaction of gut microbiota and their metabolites with different cellular components in CNS through immunological signaling. Disruption of hemostasis in gut microbiota can lead to the alternations in CNS, resulting in the progression of various CNS disorders