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Fig. 9 | Journal of Neuroinflammation

Fig. 9

From: Amlexanox attenuates experimental autoimmune encephalomyelitis by inhibiting dendritic cell maturation and reprogramming effector and regulatory T cell responses

Fig. 9

ALX minimizes the TBK1-AKT and TBK1-IRF3 signaling in splenic DCs. At the peak stage of EAE, some mice from each group were sacrificed, and their splenic tissue sections were stained with anti-CD11c (green) and anti-p-IRF3 (red) or anti-p-AKT (red) antibodies. Representative images from each group are shown. a ALX reduces the p-IRF3 signals in the splenic tissues. b, c ALX mitigates the AKT activation in the splenic tissues

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Journal of Neuroinflammation

ISSN: 1742-2094