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Table 1 Demographic and clinical data of PD patients with the list of AEs

From: Genetic variability of inflammation and oxidative stress genes does not play a major role in the occurrence of adverse events of dopaminergic treatment in Parkinson’s disease

Characteristic

All patients (N = 224)

 Sex

Female (%)

95 (42.4)

Male (%)

129 (57.6)

 Side of first symptoms

Left (%)

88 (39.3)

Both (%)

20 (8.9)

Right (%)

116 (51.8)

 Tremor-predominant PD

No (%)

41 (18.3)

Yes (%)

183 (81.7)

 Ever being treated with DAsc

No (%)

55 (25.0)

Yes (%)

165 (75.0)

 Age at diagnosis

Median (25–75%), years

62.2 (55.0–71.6)

 Disease duration

Median (25–75%), years

7.6 (3.8–14.0)

 Levodopa treatment durationb

Median (25–75%), years

6.1 (2.3–11.0)

 LED at enrolmentc, d

Median (25–75%), mg/day

970 (600–1343.63)

Adverse event

Number (%) of patients experiencing the adverse event

 Motor fluctuations

119 (53.1)

 Dyskinesia

98 (43.8)

 EDS and sleep attacks

79 (35.5)

 Visual hallucinationsa

57 (25.6)

 Nausea/vomitinga

66 (29.6)

 Orthostatic hypotensiona

84 (37.7)

 Peripheral edemaa

44 (19.7)

 Impulse control disordersa

32 (14.3)

  1. aData missing for one patient
  2. bData missing for three patients
  3. cData missing for four patients
  4. dLED calculated according to [54]