SNP | EDS and sleep attacks | Visual hallucinations | Nausea and vomiting | Orthostatic hypotension | ||||
OR (95% CI) | p value | OR (95% CI) | p value | OR (95% CI) | p value | OR (95% CI) | p value | |
NLRP3 rs35829419 | 0.70 (0.30–1.68) | 0.430 | 0.77 (0.30–2.00) | 0.593 | 0.77 (0.31–1.91) | 0.570 | 0.76 (0.33–1.76) | 0.520 |
CARD8 rs2043211 | 0.856 (0.50–1.48) | 0.581 | 0.80 (0.44–1.45) | 0.457 | 1.27 (0.71–2.27) | 0.414 | 1.01(0.59–1.74) | 0.961 |
IL1β* rs16944 | 1.25 (0.72–2.16) | 0.435 | 1.31 (0.72–2.40) | 0.380 | 0.72 (0.41–1.29) | 0.273 | 0.69 (0.40–1.18) | 0.173 |
IL1β rs1143623 | 1.19 (0.69–2.08) | 0.532 | 1.13 (0.61–2.07) | 0.702 | 0.73 (0.40–1.32) | 0.295 | 0.57 (0.32–1.00) | 0.050 |
TNF-α rs1800629 | 0.83 (0.45–1.52) | 0.547 | 0.78 (0.40–1.54) | 0.477 | 0.83 (0.44–1.57) | 0.559 | 0.98 (0.54–1.77) | 0.943 |
IL6 rs1800795 | 0.90 (0.50–1.65) | 0.740 | 0.67 (0.35–1.27) | 0.218 | 1.23 (0.64–2.36) | 0.529 | 1.34 (0.73–2.48) | 0.343 |
NOS1 rs2293054 | 1.33 (0.77–2.30) | 0.312 | 1.02 (0.56–1.86) | 0.960 | 0.84 (0.50–1.49) | 0.542 | 0.82 (0.48–1.42) | 0.480 |
NOS1 rs2682826 | 1.75 (1.00–3.06) | 0.048 | 1.25 (0.68–2.29) | 0.471 | 0.58 (0.32–1.03) | 0.064 | 1.02 (0.60–1.76) | 0.933 |
GPX1 rs1050450 | 1.13 (0.65–1.96) | 0.663 | 1.79 (0.97–3.31) | 0.061 | 0.63 (0.35–1.13) | 0.124 | 0.92 (0.54–1.59) | 0.770 |
CAT rs10836235 | 1.08 (0.56–2.05) | 0.827 | 1.65 (0.84–3.26) | 0.150 | 1.58 (0.82–3.05) | 0.174 | 1.84 (0.98–3.47) | 0.059 |
CAT rs1001179 | 1.00 (0.58–1.74) | 0.994 | 0.75 (0.41–1.37) | 0.345 | 0.76 (0.42–1.36) | 0.348 | 0.90 (0.52–1.55) | 0.693 |
SOD2 rs4880 | 1.20 (0.65–2.22) | 0.554 | 0.96 (0.50–1.85) | 0.896 | 0.51 (0.28–0.94) | 0.030 | 1.26 (0.69–2.31) | 0.450 |
SNP | Peripheral edema | Impulse control disorders | Motor fluctuations | Dyskinesia | ||||
NLRP3 rs35829419 | 0.87 (0.31–2.43) | 0.790 | 0.69 (0.20–2.42) | 0.559 | 0.74 (0.33–1.63) | 0.449 | 0.96 (0.43–2.14) | 0.919 |
CARD8 rs2043211 | 0.60 (0.31–1.17) | 0.133 | 0.55 (0.26–1.17) | 0.122 | 0.92 (0.54–1.55) | 0.744 | 1.33 (0.78–2.23) | 0.288 |
IL1β* rs16944 | 0.60 (0.31-1.17) | 0.133 | 1.72 (0.80–3.71) | 0.167 | 1.11 (0.66–1.87) | 0.700 | 1.09 (0.64–1.84) | 0.762 |
IL1β rs1143623 | 0.59 (0.29–1.19) | 0.140 | 1.10 (0.52–2.35) | 0.800 | 1.13 (0.66–1.92) | 0.665 | 1.28 (0.75–2.19) | 0.366 |
TNF-α rs1800629 | 0.85 (0.41–1.76) | 0.655 | 1.74 (0.80–3.76) | 0.162 | 1.08 (0.61–1.91) | 0.799 | 1.11 (0.63–1.97) | 0.714 |
IL6 rs1800795 | 0.95 (0.46–1.96) | 0.890 | 0.87 (0.39–1.95) | 0.731 | 0.62 (0.34–1.11) | 0.108 | 0.80 (0.45–1.43) | 0.447 |
NOS1 rs2293054 | 1.45 (0.75–2.82) | 0.270 | 0.99 (0.47–2.10) | 0.979 | 1.05 (0.62–1.78) | 0.854 | 0.73 (0.43–1.24) | 0.238 |
NOS1 rs2682826 | 1.43 (0.73–2.79) | 0.296 | 1.93 (0.88–4.22) | 0.100 | 0.89 (0.53–1.51) | 0.663 | 0.82 (0.48–1.39) | 0.459 |
GPX1 rs1050450 | 0.75 (0.39–1.46) | 0.400 | 0.79 (0.37–1.67) | 0.531 | 1.55 (0.92–2.63) | 0.103 | 1.18 (0.70–2.01) | 0.533 |
CAT rs10836235 | 0.70 (0.30–1.63) | 0.410 | 1.39 (0.60–3.23) | 0.446 | 1.15 (0.62–2.14) | 0.663 | 1.39 (0.75–2.59) | 0.301 |
CAT rs1001179 | 0.32 (0.15–0.68) | 0.003 | 0.67 (0.31–1.45) | 0.314 | 0.92 (0.54–1.55) | 0.750 | 1.28 (0.75–2.18) | 0.362 |
SOD2 rs4880 | 0.75 (0.37–1.52) | 0.422 | 0.89 (0.40–2.00) | 0.777 | 1.25 (0.70–2.22) | 0.456 | 1.04 (0.58–1.86) | 0.897 |