Cerebrospinal fluid biomarkers for predicting development of multiple sclerosis in acute optic neuritis: a population-based prospective cohort study

Table 2 Multivariate logistic regression modeling for the candidate and routine biomarkers and a combined biomarker model, which combines candidate and routine biomarkers into one model

	Number of observations	Likelihood ratio χ2	p value	Adjusted McFadden R²	Hosmer-Lemeshow’s p value	Area under ROC curve	AUC 95% CI
Experimental biomarkers
IL-10 NF-L CXCL13	33	17.26	0.0006	0.15	0.66	0.89	0.77–1.00
Routine biomarkers
OCB Leukocytes IgG index	38	16.33	0.0010	0.16	0.86	0.86	0.74–0.98
Full model	33	21.53	0.0015	0.10	0.66	0.90	0.78–1.00

ISSN: 1742-2094