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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: FTY720 controls disease severity and attenuates sciatic nerve damage in chronic experimental autoimmune neuritis

Fig. 2

Electrophysiological changes in c-EAN rats treated with FTY720 or vehicle at 13, 18, 40, and 60 dpi. a Sensory nerve action potential (SNAP) conduction velocity of the caudal nerve. b Sciatic motor nerve distal CMAP latency. c CMAP amplitudes obtained after proximal stimulation of the sciatic nerve. d CMAP amplitude ratio of distal values/proximal values. Mean values, SEM, and p values are indicated. *p values refer to difference between FTY720-treated group and the vehicle-treated group at the same dpi (*p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001). ψp values refer to the difference in the vehicle- or FTY720-treated group when compared to 13 dpi (ψp < 0.05; ψψp < 0.01; ψψψp < 0.001; ψψψψp < 0.0001). Φp values refer to the difference in the FTY720-treated group when compared to 18 dpi (ΦΦΦp < 0.001). n = 5 rats/group. n, number of rats

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