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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Urolithin A attenuates memory impairment and neuroinflammation in APP/PS1 mice

Fig. 2

UA alleviated neuronal death and enhanced hippocampal neurogenesis in APP/PS1 mice. a, b Immunohistochemical analysis of NeuN+ cells in the CA1 regions of different treatment groups. Scale bar = 100 μm. n = 8–10 mice per group, three sections per animal. cf Quantitative analysis of TUNEL-reactive cells in the CA1 and dentate gyrus (DG) regions of the hippocampus. Scale bar = 200 μm. n = 8–10 mice per group, three sections per animal. g, h Quantitative analysis of TUNEL-reactive cells in the frontal cortex. Scale bar = 200 μm. n = 8–10 mice per group, three sections per animal. Data are presented as the mean ± SEM. *P < 0.05 and **P < 0.01. WT wild-type, UA urolithin A

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