Fig. 7
From: Urolithin A attenuates memory impairment and neuroinflammation in APP/PS1 mice
Effects of UA on the protein expression of p-AMPK, p-P65NFκB, p-P38MAPK, and Bace1, APP in the cortex and hippocampus of APP/PS1 mice. Western blot analysis of a p-AMPK in the cortex, b p-AMPK in the hippocampus, c p-P65NFκB in the cortex, d p-P65NFκB in the hippocampus, e p-P38MAPK in the cortex, f p-P38MAPK in the hippocampus, g Bace1 in the cortex, h Bace1 in the hippocampus, i APP in the cortex, and j APP in the hippocampus. For all the above Western blots, the relative optical density was normalized to GAPDH or β-Actin; n = 4; **P < 0.01. WT wild-type, UA urolithin A. The fold change refers to the ratio of p-AMPK/AMPK, p-P65NF-κB/P65NF-κB, p-P38MAPK/P38MAPK, BACE1/GAPDH, and APP/β-Actin compared to WT group