Fig. 4

The mean percentage response of CCI-operated (green; n = 6) and sham-operated (orange; n = 6) mice on day 21 post-surgery (*p < 0.05) is shown for hair weights of 1 (0.04 g), 2 (0.07 g), 3 (0.16 g), 4 (0.4 g), 5 (0.6 g), and 6 (1.0 g). Contralateral hind paw shows no difference in mean percentage response between a CCI- and b sham-operated animals. Ipsilateral hind paw shows significant higher mean percentage response of CCI-operated animals in hair weight 1 g (c), compared to d sham-operated (*p < 0.05). Within CCI-treated animals, the mean percentage response was significantly higher in 0.4, 0.6, and 1 g hairs, compared to 0.04 g hair (^#p < 0.05)